The course applies both theoretical and practical approaches to the understanding of the main biological mechanisms driving embryo development. Tissue spatial organization is examined at the microscopic as well as macroscopic level. Beside the course will illustrate the most advanced veterinary biotechnological methods currently in use. Particular emphasis will be given to methods for stem cell derivation and to the main techniques used in cell therapy and translational medicine.
Expected learning outcomes
At the end of the course the student acquires: - Knowledge and understanding of the various anatomical districts of the body, their function and interactions/regulations as well as the process regulating their differentiation. - Ability to apply knowledge and understanding in critically read the textbooks and use an improved communication using scientific terminology. - Practical skills in the preparation, staining and interpretation of histological sections
Lesson period: Second semester
(In case of multiple editions, please check the period, as it may vary)
Differentiation of the gonads (egg or hen first?) Oocyte and ovulation maturation (a packaging miracle) Spermatogenesis and capacitation of the spermatozoon (fearless messengers) Fertilization (close encounters of the 1st type) Embryo development and tissue differentiation (genetics proposes and epigenetics disposes) Cellular divisions (I make myself into four) Blastulation (... and much more) Implantation (conquering the unknown) Origin and specification of embryonic layers (one, someone, one hundred thousand) Placentation (a declaration of independence) Genetic manipulation: nuclear transplantation and transgenesis (science and science fiction) Stem cell derivation (time travelling) The epithelia and their functional characteristics (the dress makes the monk) The tissues of support, nutrition and protection (a matter of substance) Muscle and its structure (microarchitecture masterpieces) Nervous tissue (life is electricity) General organization of the body (planning is everything) The skeleton and the joints (thrust, structure and stress ...) The digestive system and its glands (sailing stormy seas) The central and peripheral nervous system (a wired system) The urinary and genital apparatus (water and life) The endocrine system (fine tuning) The skin and skin appendages (the hair is lost but not the vice) The respiratory system (until the last breath) The circulatory system (round trip) Spleen and lymphatic organs (one-way trip)
Practicals: each student will have at his disposal a microscope station for practical observations of slides and will be able to analyze anatomical preparations related to the topics listed below. The epithelial barrier Connective tissue types Muscle tissue Nervous tissue The skeleton and the joints Digestive tract of the digestive system and its glands The peripheral central nervous system The urinary tract The testis The male genital tract The ovary The female genital tract The endocrine system The skin and skin appendages The breast The respiratory system The heart The circulatory system Spleen and lymphatic organs
Prerequisites for admission
No preliminary knowledge is required
Lectures and practical classes consisting in: a. the use of individual microscope for the examination of istological samples; b. the preparation of an histological sample from collection to the staining; c. dissection of a rat and a mouse
[Materiale di riferimento]: H.E. Konig e H.G. Liebich "Anatomia dei Mammiferi Domestici" - Piccin L.C. Junqueira e J. Carneiro "Compendio di Istologia" - Piccin Drews U. Testo atlante di embriologia, Zanichelli, Bologna 1996 Handouts
Assessement methods and criteria
Written test of 40 multiple-choice questions (5 answers) with the possibility of choosing only one or more correct answers. The final mark is expressed in thirtieths. Exam are in number of 8 in the Academic year and take place in the months of January, February, April, June, July, September, October and December. There are no additional calls for out-of-course. To take the exam, it is essential to register for the exam through the ONLINE SIFA service of the University and must have attended not less than 75% of the hours both theoretical and practices.