Drug analysis 2 and laboratory of drug analysis 2

A.Y. 2019/2020
Lesson for
10
Max ECTS
112
Overall hours
SSD
CHIM/08
Language
Italian
Learning objectives
The lectures and the individual laboratory training of Drug Analysis II and Laboratory of Drug Analysis II are aimed at providing the student with the knowledge and the practice of chemical and instrumental methods for the identification of the substances reported in European Pharmacopoeia monographs, improving his critical skills in approaching analytical challenges in the pharmaceutical field.
At the end of the course, the student will be able to understand the theoretical aspects of the principal techniques of identification and analysis of pharmaceutical substances and to properly apply them so as to answer the questions of the conclusive written examination.

Course structure and Syllabus

Linea Unica
Active edition
Yes
Responsible
DRUG ANALYSIS 2
CHIM/08 - PHARMACEUTICAL CHEMISTRY - University credits: 6
Lessons: 48 hours
Professor: Pallavicini Marco
LABORATORY OF DRUG ANALYSIS 2
CHIM/08 - PHARMACEUTICAL CHEMISTRY - University credits: 4
Single bench laboratory practical: 64 hours
Shifts:
Turno 1
Professors: Bolchi Cristiano, Romeo Sergio
Turno 2
Professor: Villa Stefania
Turno 3
Professor: Bolchi Cristiano
LABORATORY OF DRUG ANALYSIS 2
Syllabus
Recognition of organic and metallorganic substances of pharmaceutical interest
Introduction to the analysis of organic compounds. Organoleptic examination. Combustion tests and residue analysis, recognition of metals in organometallic substances registered in the F.U.
Preparation of Lassaigne's solution for the detection of nitrogen, sulfur, halogens, phosphorus. Solubility of organic substances: solubility in water and reactive solvents; classification of substances based on their solubility.
Assays for the recognition of functional groups in organic substances: alcohols, aldehydes, ketones, polyalcohols, sugars, carboxylic acids, α-oxyacids, phenols, amines, amino acids, esters, amides.
Examination of the substances registered in the F.U. Pharmaceutical substance classes: general and specific tests for alkaloids, sulpha, xanthine, glycosides, various substances.
Recognition of inorganic substances of pharmaceutical interest.
Lesson period
First semester
Lesson period
First semester
Assessment methods
Esame
Assessment result
voto verbalizzato in trentesimi