Organic Chemistry 2 and Organic Chemistry Laboratory

A.Y. 2018/2019
10
Max ECTS
112
Overall hours
SSD
CHIM/06
Language
Italian
Course syllabus and organization

Linea AK

Linea AK
Responsible
Lesson period
First semester
Organic Chemistry 2
Syllabus
1- Amino acids and peptides: chemical-physical properties and synthesis of amino acids; protecting groups and peptide synthesis.
2- Aromatic compounds. Chemistry of benzene and naphthalene, aromaticity and substituent effects. Mechanisms of electrophilic substitution (halogenation, nitration, sulfonation, Friedel-Craft's alkylation and acylation) and nucleophilic substitution (SnAr, benzyne intermediate). Diazonium salts: synthesis and reactivity. Some classes of compounds will be studied in detail according to their particular importance.
3- Sulfur compounds
3- Enol and enolate chemistry, enamines: termodinamic and kinetic aspects of enolization, enolate and enamines formation and stabilization; synthetic application of base and acid catalyzed aldol reactions, Claisen and Dieckmann condensations. Alkylations, acetoacetic and malonic reactions. Mannich, Henry, Knoevenagel, Wittig reactions and Robinson annulation. Theoretical aspects and reactivity of electron-poor alkenes.
4- Heterocyclic compounds and their nomenclature. A general overview on the reactivity of the most important 5-member (pyrrole, thiophene, furan, oxazole, imidazole, thiazole, isoxazole) and 6-member (pyridine and quinoline) heterocyclic nucleus and their syntheses.
5- Some lessons will concern theoretical and practical exercises.
Organic Chemistry 2
CHIM/06 - ORGANIC CHEMISTRY - University credits: 6
Lessons: 48 hours
Professor: Gelmi Maria Luisa
Organic Chemistry Laboratory
CHIM/06 - ORGANIC CHEMISTRY - University credits: 4
Single bench laboratory practical: 64 hours
Shifts:
Turno 1
Professor: La Rosa Concetta
Turno 2
Professor: Gelmi Maria Luisa

Linea LZ

Linea LZ
Responsible
Lesson period
First semester
Organic Chemistry 2
Syllabus
1- Amino acids and peptides: chemical-physical properties and synthesis of amino acids; protecting groups and peptide synthesis.
2- Aromatic compounds. Chemistry of benzene and naphthalene, aromaticity and substituent effects. Mechanisms of electrophilic substitution (halogenation, nitration, sulfonation, Friedel-Craft's alkylation and acylation) and nucleophilic substitution (SnAr, benzyne intermediate). Diazonium salts: synthesis and reactivity. Some classes of compounds will be studied in detail according to their particular importance.
3- Sulfur compounds
3- Enol and enolate chemistry, enamines: termodinamic and kinetic aspects of enolization, enolate and enamines formation and stabilization; synthetic application of base and acid catalyzed aldol reactions, Claisen and Dieckmann condensations. Alkylations, acetoacetic and malonic reactions. Mannich, Henry, Knoevenagel, Wittig reactions and Robinson annulation. Theoretical aspects and reactivity of electron-poor alkenes.
4- Heterocyclic compounds and their nomenclature. A general overview on the reactivity of the most important 5-member (pyrrole, thiophene, furan, oxazole, imidazole, thiazole, isoxazole) and 6-member (pyridine and quinoline) heterocyclic nucleus and their syntheses.
5- Some lessons will concern theoretical and practical exercises.
Organic Chemistry 2
CHIM/06 - ORGANIC CHEMISTRY - University credits: 6
Lessons: 48 hours
Organic Chemistry Laboratory
CHIM/06 - ORGANIC CHEMISTRY - University credits: 4
Single bench laboratory practical: 64 hours
Shifts:
Turno 1
Professor: Rossi Elisabetta
Turno 2
Professor: Erba Emanuela