Biomarkers in animal models

A.Y. 2015/2016
8
Max ECTS
48
Overall hours
SSD
AGR/18 AGR/19 VET/05
Language
English
Learning objectives
Undefined
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Responsible
Lesson period
Second semester
ATTENDING STUDENTS
Diagnostic tools in animal infectious diseases
Course syllabus
Cultivation and identification of the main pathogens in animals
PCR and molecular methods
Serological methods: IFA, ELISA, HAE
Laboratory techniques to test DNA-damage in animal models
Course syllabus
The main topic of the course concerns the introduction to fundamental bases of oxidative stress cell exposure and application of biomarkers based assays able to verify in vivo oxidative damage and anti-oxidant capacity. Mostly, the course examines the development of reactive intermediates which can covalently bind to DNA, resulting in bulky addition products called "adducts." DNA.
Lectures
Causes and occurrence of oxidative stress damage.
Evaluation of total anti-oxidant capacity and repairing mechanisms.
Application of biomarkers for the screening and monitoring of oxidative status.
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA.
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems.
Biomarkers in animal nutrition
Course syllabus
AIM OF THE COURSE:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status o fan essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
Lectures
Nutritional (feed) behavior
Nutritional status evaluation
Vitamins status biomarkers
Antioxidant status biomarkers
Mineral status biomarkers


Tutorials/ractice training
Database use
Laboratory activities
Journal club
NON-ATTENDING STUDENTS
Diagnostic tools in animal infectious diseases
Course syllabus
Cultivation and identification of the main pathogens in animals
PCR and molecular methods
Serological methods: IFA, ELISA, HAE
Laboratory techniques to test DNA-damage in animal models
Course syllabus
The main topic of the course concerns the introduction to fundamental bases of oxidative stress cell exposure and application of biomarkers based assays able to verify in vivo oxidative damage and anti-oxidant capacity. Mostly, the course examines the development of reactive intermediates which can covalently bind to DNA, resulting in bulky addition products called "adducts." DNA.
Main topics:
Causes and occurrence of oxidative stress damage.
Evaluation of total anti-oxidant capacity and repairing mechanisms.
Application of biomarkers for the screening and monitoring of oxidative status.
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA.
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems.
Biomarkers in animal nutrition
Course syllabus
AIM OF THE COURSE:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status o fan essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
Lectures
Nutritional (feed) behavior
Nutritional status evaluation
Vitamins status biomarkers
Antioxidant status biomarkers
Mineral status biomarkers


Other skills
database use
journal club
Biomarkers in animal nutrition
AGR/18 - ANIMAL NUTRITION AND FEEDING - University credits: 3
Lessons: 18 hours
Professor: Pinotti Luciano
Diagnostic tools in animal infectious diseases
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 3
Lessons: 18 hours
Professor: Martino Piera Anna
Laboratory techniques to test DNA-damage in animal models
AGR/19 - ANIMAL SCIENCE - University credits: 2
Lessons: 12 hours