Biomenbranes

A.Y. 2015/2016
6
Max ECTS
48
Overall hours
SSD
BIO/09
Language
Italian
Learning objectives
Fornire gli strumenti culturali e metodologici per l'analisi molecolare della funzionalità delle proteine di membrana, con particolare riguardo ai processi di trasporto.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Lesson period
First semester
Course syllabus
Some aspects of membrane biophysics. Role of lipid and protein components. Membrane microdomains and lipid-protein interactions.
Structural and functional features of membrane proteins with respect to transmembrane domains and presence of alpha helix and/or beta sheets. Structure-function relationship. Determination of function by means of structural homology analysis. Functional domains: homo- and heteromultimers.
Membrane proteins multifunction. Channel-type behaviour of transport proteins. Protein translocation between cell membrane and cytoplasm in different cellular conditions. Methods used for the characterization of membrane proteins.
Examples of membrane transports mediated by carrier proteins, ionic channels, V-ATPases, P-ATPases, ABC-transporters in animal and plant cells will be discussed.
Papers related to the topics described will be analysed.
BIO/09 - PHYSIOLOGY - University credits: 6
Lessons: 48 hours
Professors: Barbuti Andrea Francesco, De Michelis Maria Ida
Professor(s)
Reception:
to be arranged by email
Torre A 6th floor