Experimental and clinical transplantation

A.Y. 2015/2016
6
Max ECTS
48
Overall hours
SSD
BIO/14 MED/18 MED/43 VET/05
Language
Italian
Learning objectives
The course is designed to investigate organ transplantation in its multiple aspects, ranging from experimental models, clinical pharmacology, and legislation to clinical transplantation. It represents the most clear expression of how the multidisciplinary approach was and is crucial for the optimal clinical outcome of organ transplants and the excellent results achieve by this therapy in the last decade.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Responsible
Lesson period
Third trimester
Chirurgia generale
Course syllabus
: We will analyze in detail the experimental models of transplantation used for development of new drugs in the field of transplantation, . Regenerative medicine in organ transplantation will be presented with a particular focus in lung transplantation and in the possibility to manipulate the organ before transplantation in order to obtain a fully functional transplant. The role of liver bio-reactors and the state of the art of this device as a bridge for transplantation will be also presented in detail.In the field of organ transplantation, will be overview the most common organ transplants performed in Italy, and the important role played by the biotechnologist in this area will be emphasized. In particular, from the identification of the ideal donor to the virological and tumoral screening to the early diagnosis of infections and malignancies in transplant recipients. Stages are planned at the Organ procurement center for inter-regional distribution and retrieval of organs and will be discussed its role within the Italian transplant network.
Malattie infettive degli animali domestici
Course syllabus
We will provide some basics of animal immunology and legal regulation for animal experimentation. We also discusses the surgical models of inflammation and autoimmune diseases.
Medicina legale
Course syllabus
Will be presented the current legislation in organ, tissue and cell transplants with respect to E.E.C. guidelines in terms of human tissues and cells. Will be discussed the role of bio-banks and the problems associated with the identification of the sample (traceability) and anonymity, the properties of the biological material and the prohibition of marketing. The legal protection of biotechnological inventions will be discuss.
Farmacologia
Course syllabus
The main immunosuppressive drugs and their use in the clinical practice will be presented in order to achieve the long term survival of the graft.
Chirurgia generale
MED/18 - GENERAL SURGERY - University credits: 3
Lessons: 24 hours
Professors: Ferraresso Mariano, Gatti Stefano
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 1
Lessons: 8 hours
Professor: Marelli Ornella
Malattie infettive degli animali domestici
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 1
Lessons: 8 hours
Professor: Riva Federica
Medicina legale
MED/43 - FORENSIC MEDICINE - University credits: 1
Lessons: 8 hours