Medicinal Chemistry 1

A.Y. 2015/2016
10
Max ECTS
80
Overall hours
SSD
CHIM/08
Language
Italian
Learning objectives
Undefined
Expected learning outcomes
Undefined
Course syllabus and organization

Linea A-K

Lesson period
Second semester
Course syllabus
The programme contains a general section and a systematic section. The latter, besides showing the main goals achieved by the medicinal chemistry research, is meant to give a practical application of the concepts presented in the general section.
The two sections can be summarized as follows:

General Section
Aspects and aims of the medicinal chemistry research. Drug design: modern and traditional approach. New technologies. Prodrugs. Receptors and enzymes. Drug-target interaction. Pharmacophore. Pharmacokinetics (ADMET), general concepts. Chirality in medicinal chemistry. Intellectual property and market.

Systematic section
Chemotherapeutics: general considerations and classification. Antimetabolites. Sulfonamides. Antitubercolosis drugs. Antimalarial drugs. Antifungal drugs. Quinolone derivatives. Antibiotics: inhibitors of the bacterial wall synthesis, protein synthesis inhibitors, nucleic acid synthesis inhibitors, compound which act on the bacterial cell membrane. Antitumor drugs. Antiviral drugs. Antidiabetics. Steroids. Vitamines. Natural compounds as a source for new drugs.

At the end of the course the student will sustain a written and an oral exam.
CHIM/08 - PHARMACEUTICAL CHEMISTRY - University credits: 10
Lessons: 80 hours
Professor: Barlocco Daniela

Linea L-Z

Responsible
Lesson period
Second semester
CHIM/08 - PHARMACEUTICAL CHEMISTRY - University credits: 10
Lessons: 80 hours
Professor: Valoti Ermanno
Professor(s)