Molecular pharmacology and immunology

A.Y. 2015/2016
6
Max ECTS
48
Overall hours
SSD
BIO/14 MED/04
Language
Italian
Learning objectives
Lo studente apprenderà in dettaglio i meccanismi d'azione a livello cellulare e molecolare dei più recenti farmaci in commercio e verranno prospettati possibili nuovi bersagli terapeutici. Inoltre l'insegnamento trattera' dei meccanismi alla base delle patologie del sistema immunitario e le possibili terapie. Si vedra' come dalla identificazione dei meccanismi molecolari della risposta immune si possano disegnare nuovi farmaci.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Lesson period
First semester
Course syllabus
Pharmacogenetic
Pharmacology of signal transduction.
Kinases inhibitors as antitumor drugs.
Monoclonal antibodies and soluble receptors as drugs
Transporters as target for drugs
Immunosuppressants and immunostimulants
Endocannabinoid system
Excitatory aminoacids and excitotoxicity
Physiopathology of pain and analgesics
G protein receptor regulation
Chemotherapy of microbial diseases and drug resistance
Chemotherapy of neoplastic diseases

Autoimmune diseases.
Allergy
Vaccines.
Immunological reactions against tumors and transplanted organs.
Heart and bone marrow transplantation.
Congenital and acquired immunodeficiency.
AIDS and Kaposi sarcoma
BIO/14 - PHARMACOLOGY - University credits: 0
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 0
Lessons: 48 hours
Professor(s)
Reception:
Monday, 14.30-16.30; Thursday, 14.30-15.30
via Vanvitelli 32