To acquire the diffusion-MRI and the functional-MRI techniques. Basic properties of nanomagnetic particles and their applications to medicine. To acquire know-how in the synthesis of nanoparticles and nanostructures and in techniques of microscopy and spectroscopy applied at the nanoscale
Expected learning outcomes
Lesson period: First semester
(In case of multiple editions, please check the period, as it may vary)
I part - A. Lascialfari History of magnetism in medicine. Recalls of MRI principles. Images reconstruction. Functional MRI. Diffusion-MRI. Nanomagnetism and magnetic techniques. MRI contrast agents. Magnetic transport (in biological systems). Magnetic hyperthermia in medicine. Hyperthermic agents.
II part - C. Lenardi Method of synthesis of nanoparticles for controlled biomolecules release (drug delivery). Growth of nanostructures: bottom-up and top-down approaches for applications in biology (protein and cell arrays). Electron microscopy SEM and TEM. AFM Microscopy. X-rays spectro-microscopy. Bioimaging techniques with fluorescent probes: 2-photons confocal microscopy, STED, FRET, FRAP, TIRF. Lab-on-chip and Cell-on-chip systems for biomedical applications.