Organic chemistry lab

A.Y. 2016/2017
10
Max ECTS
160
Overall hours
SSD
CHIM/06
Language
Italian
Learning objectives
Il corso di laboratorio ha come obiettivo di insegnare agli studenti le operazioni fondamentali che vengano effettuate di routine in un laboratorio di chimica organica, con particolare attenzione alle norme di sicurezza. Si propone inoltre di insegnare le principali tecniche di separazione e purificazione di composti organici. Vengono infine proposti alcuni esempi di reazioni organiche, con caratterizzazione dei prodotti ottenuti mediante punto di fusione e spettroscopia IR e analisi dei prodotti mediante lettura di spettri NMR.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Responsible
Lesson period
year
Unit: Laboratory of organic chemistry 2
Course syllabus
Course content
(1° semester) - Luigi Lay ; 5 credits
1. Safety and accident prevention in the chemical laboratory,
2. Main techniques of isolation and purification of organic compounds (extraction, crystallisation, simple distillation, fractional distillation, chromatography),
3. Introduction to IR spectroscopy,
4. Experimental aspects of some fundamental organic reactions, evaluation of the purity grade of the obtained products through TLC and mp.
5. Lab experiments will be selected in order to further consolidate experimentally the arguments of the theoritcal lessons.
2° semester - Maurizio Benaglia; 5 credits
Selected examples of chemical transformations and functional groups conversions are presented, including reactions related to aromatic chemistry: the synthesis of an aromatic amide, an example of aromatic heterocycle synthesis, a reaction sequence on an aromatic ring, the use of diazonium salt in the preparation of an indicator, a phase transfer-catalyzed transformation, an oxidation reaction.
Finally the determination of an unknown carbonyl compound, the separation of a mixture of two unknown compounds, their recognition and preparation of their suitable derivatives are the topics of the last week of work in lab.
The characterization of the products will be accomplished by melting point, IR spectroscopy and, if the case, with chiral product by measurement of the optical rotatory power.
The common purification techniques for organic compounds are employed: crystallization, acid/base separation, distillation under vacuum, chromatographic separation on a silica gel column.

Reference material
M.D. Ischia: La Chimica Organica in Laboratorio, Piccin, Padova, 2002

Website: http://mbenaglialco.ariel.ctu.unimi.it/v1/home/Default.aspx
Unit: Laboratory of organic chemistry 1
CHIM/06 - ORGANIC CHEMISTRY - University credits: 5
: 0 hours
Practicals: 16 hours
Laboratories: 64 hours
Shifts:
Professors: Belvisi Laura, Lay Luigi
Corso A
Professor: Lay Luigi
Corso B
Professors: Belvisi Laura, Polito Laura
Unit: Laboratory of organic chemistry 2
CHIM/06 - ORGANIC CHEMISTRY - University credits: 5
: 0 hours
Practicals: 16 hours
Laboratories: 64 hours
Professors: Benaglia Maurizio, Bossi Alberto, Orlandi Simonetta, Silvani Alessandra
Shifts:
Professor: Benaglia Maurizio
Corso A
Professors: Benaglia Maurizio, Orlandi Simonetta
Corso B
Professors: Bossi Alberto, Silvani Alessandra