System pharmacology

A.Y. 2018/2019
6
Max ECTS
48
Overall hours
SSD
BIO/14
Language
Italian
Learning objectives
At the end of the course the student has learned that drugs are developed in order to therapeutically treat disease on the basis of the pathological processes present, but also as tools to be applied in the research to understand the pathological basis of diseases.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Course syllabus
Goals:
At the end of the course the student has learned that drugs are developed in order to therapeutically treat disease on the basis of the pathological processes present, but also as tools to be applied in the research to understand the pathological basis of diseases


Program:
The main general pharmacology concepts will be refreshed (they are mainly discussed in the first level course) and thereafter the different classes of drugs will be illustrated in detail in relation to their application in therapy or as investigational tools.

General pharmacology
Drugs Adsorption, Distribution, Metabolism, Elimination, Farmacokinetics
Receptors and Transporters, Dose-Response

Special pharmacology
Neurotransmitters, a general view, The Autonomic Nervous System
Acetilcholine- Miorelaxant drugs, Catecholamines, Serotonin,Histamine, Nitric Oxide,Aminoacids,Purines
CNS Acetilcholine

Drugs of the Central nervous system
General and Local Anaesthetics
Degenerative Diseases Alzheimer, Huntington Chorea, ALS, Parkinson
Diseases of Behavior: antipsychotic drugs, Psychotomimetics, Psychostimulants, Antidepressants, Anxiolytics
Central myorelaxant drugs
Pain and analgesia: Opiates and other analgesics
Anticonvulsants

Drugs of inflammation
Steroids
Nonsteroidal anti-inflammatory drugs
Histamine

The Cardiovascular System:
Diuretics, Vasodilators, drugs for the treatment of Ischemia and heart failure, Antiarrhythmic drugs, antihypertensive drugs

Drugs of the Respiratory system
Asthma

Drugs of the Gastrointestinal system
Peptic ulcer and drugs for acid related disorders
The endocrine System: a general view

Immunoppressant drugs

Chemotherapy
Antibacterial drugs
Antiviral drugs




Referece material
Katzung B.G.: "Pharmacology 9th Ed."; Lange Medical Publications
Rang H.P., Dale M.M., Ritter J.M.: "Pharmacology 4th Ed"; Churchill Living Stone
For reference: Goodman and Gilman's: "The pharmacological basis of therapeutics, 11th Ed."; Pergamon Press.


Final examination:
1. multiple choice questions + a few long answer questions in order to better assess the comprehension of the students, his/her ability to make connections and to write in a correct scientific language

Suggested prerequisites
Human Physiology, Human Anatomy

Teaching:
frontal lessons and seminars on specific topics

Language:
Italian

Other informations
First day of course- teacher's Ariel site

WEB pages
http://psacerdote.ariel.ctu.unimi.it/
BIO/14 - PHARMACOLOGY - University credits: 6
Lessons: 48 hours
Professor(s)
Reception:
Monday, 14.30-16.30; Thursday, 14.30-15.30
via Vanvitelli 32