The course intends to provide knowledge on the endocrine systems under physiopathological conditions and their interaction with phytohormones. The unit of Hormones/Phytohormones will discuss the general concepts of endocrinology, with a particular view on endocrine axes and the effects of phytohormones, such as phytosterols and phytoestrogens, on the systems correlated with them. The unit of Metabolic Pathologies will provide knowledge on metabolic biomarkers and pathologies, such as obesity, diabetes mellitus, metabolic syndrome, dyslipidemia, eating disorders and bone metabolism.
Expected learning outcomes
At the end of the teaching the student must demonstrate a solid knowledge of endocrinology and phytohormones as well as of metabolic pathologies.
Lesson period: First semester
(In case of multiple editions, please check the period, as it may vary)
Knowledges in anatomy, physiology and biochemistry are needed
Assessment methods and Criteria
Oral exams are planned for the two didactic units. The final evaluation will be the result of the mean of the single votes
Introduction to endocrinology Endocrine systems: peptidic hormones and molecular mechanisms Endocrine systems: steroids and molecular mechanisms Hypothalamus, hypophysis and related hormones Growth axis Adrenal axis Thyroid axis Pancreas, its hormones and glucose metabolism Mineral metabolism Gonadal axis Phyto-hormones and differences between animal and vegetal hormones Phytosterols and therapeutic indications: cardiovascular diseases Phytoestrogens: classification, biosynthesis, chemical and pharmacological properties Phytoestrogens and therapeutic indications Nutraceuticals, functional foods and xenobiotics
Williams Textbook of Endocrinology¸ Melmed, Polonsky, Larsen, Kronenberg; Elsevier; ISBN 978-1-4377-0324-5 Greenspan & Strewler, Endocrinologia Generale e Clinica; Piccin; ISBN 88-299-1565-3
Metabolic biomarkers Eating disorders Hormones and pregnancy Dyslipidemia Body composition evaluation Molecular aspects of the obesity Obesity, nutrition and genetics Bone metabolism Thyroid metabolism Metabolism and aging