A.Y. 2020/2021
Overall hours
Learning objectives
The course is designed to present essential concepts of pathological processes and altered health states. Thus, the main objective is to study the pathological mechanisms beyond the systemic diseases paying special attention to the etiology (cause of the disease) and the pathogenesis (origin and development of a disease). The fields covered will be: atherosclerosis, cardiocirculatory system, neurodegenerative diseases, thyroid, diabetes mellitus, liver, microbiota and immune system.
Brief summary:
1. Classification of systemic and organ specific diseases and how they manifest clinically.
2. Identification of abnormal physiologic conditions causing the disease.
3. Study of the etiology and pathogenesis of diseases, with the final goal to identify specific pathways that can be targeted by biotechnological approaches.
Expected learning outcomes
Identification of the different etiologies and pathogenetic mechanism correlated to the pathological processes: atherosclerosis, cardiocirculatory system, neurodegenerative diseases, thyroid, diabetes mellitus, liver and microbiota.
Ability to translate the theoretical approach to a more practical one. To pursue this object, the students will face with recent research articles which have addressed the mechanisms beyond the pathologies studied.
To acquire the ability to relate these essential basic pathological processes to the pathogenesis of common and important diseases.
To correlate clinical features with the causes and mechanisms of disease.
Course syllabus and organization

Single session

Lesson period
First semester
Lessons will be delivered on line and recorded to be immediately available. All the learning supplies will be available on ARIEL platform. The final evaluation will be performed at distance by using digital platforms.
Course syllabus
- Liver-related diseases
- Hepatitis
- Genetic determinants of non alcoholic fatty liver disease
- Diabetes
- Atherosclerosis
- Hypertension
- Microbiome
- Thyroid
- Alzheimer
- Anemia and blood related diseases
- Prions
- Immunity
Prerequisites for admission
Physiology: endocrine system, cardiovascular system, lymphatic system

Anatomy: The heart, the liver, the thyroid, the pancreas, the gastrointestinal tract
Teaching methods
Standard teacher-based lessons
Teaching Resources
(1) Microsoft Teams recordings (Ariel webpage)

(2) All the slide are present on Ariel webpage

(3) Patologia Generale e Fisiopatologia, Fabio Celotti, 2013. Edises

(4) Robbins. Fondamenti di patologia e di fisiopatologia di Vinay Kumar, Abul K. Abbas, J. C. Aster
Assessment methods and Criteria
Oral test to evaluate students' knowledge of the fundamental concepts of the subject. Positive marks are from 18 to 30 cum laude.
Lessons: 48 hours