Pharmacological biomolecular sciences, experimental and clinical

Dottorati
Doctoral programme (PhD)
A.Y. 2018/2019
Study area
Science and Technology
Doctoral programme (PhD)
3
Years
Milano
English
PhD Coordinator
The doctoral programme, a third cycle programme, makes the most of the multidisciplinary knowledge of the teaching staff to train biomedical experts in the most modern aspects of pharmacological research. In particular, the areas of interest are:
Basic research: the study of key mechanisms and molecules in physiopathological processes to identify new pharmacological targets and/or new markers predictive of disease and therapeutic effectiveness. Research involves: 1) the analysis of molecular and cellular aspects of complex physiological processes, 2) the study of pathogenic mechanisms in diseases, 3) the study of biological markers of use in translation of preclinical research to humans.
Research applied to the pharmacological-toxicological study of active ingredients: 1) analisi analysis of the activity of active principles, including biological drugs under development or in clinical use, 2) analysis of foods, food supplements and therapeutic plant derivatives, 3) analysis of xenobiotic activity.
Research applied to the creation of innovative systems for studying pathologies and developing drugs and evaluation of their effects on the population. Basic research on: 1) the development of cellular and animal models also through genetic engineering methodologies, 2) optimising preclinical protocols for simple and complex diseases, including co-morbidities 3) in silico approaches to the study of new drug-toxicology targets, 4) the use of databases and population studies also to assess drug use and outcomes in terms of clinical events.
Technical-scientific collaboration for revising documentation on active compounds and plant protection products and for drug safety and with other clinical centres.
In conclusion, students will develop competencies applicable to various areas of academic and industrial research, allowing effective "bench to bed" translation and a multidisciplinary approach essential for public health, with significant socio-economic impact on health.
Classi di laurea:
LM-6 Biologia,
LM-7 Biotecnologie agrarie,
LM-8 Biotecnologie industriali,
LM-9 Biotecnologie mediche, veterinarie e farmaceutiche,
LM-13 Farmacia e farmacia industriale,
LM-17 Fisica,
LM-18 Informatica,
LM-21 Ingegneria biomedica,
LM-41 Medicina e chirurgia,
LM-42 Medicina veterinaria,
LM-55 Scienze cognitive,
LM-60 Scienze della natura,
LM-61 Scienze della nutrizione umana,
LM-69 Scienze e tecnologie agrarie,
LM-70 Scienze e tecnologie alimentari,
LM-75 Scienze e tecnologie per l'ambiente e il territorio,
LM-82 Scienze statistiche,
LM/SNT1 Scienze infermieristiche e ostetriche,
LM/SNT2 Scienze riabilitative delle professioni sanitarie,
LM/SNT3 Scienze delle professioni sanitarie tecniche,
LM/SNT4 Scienze delle professioni sanitarie della prevenzione.

Courses list

March
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Animal welfare and non-animal testing 2 14 English
Nutrition and nutraceutics: analytical, experimental, clinical and regulatory aspects 2 14 English
April
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Chronic viral infections and the development of antiviral agents
2 14 English
May
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Advanced approaches to neurodegeneration: focus on early stages 2 14 English
Genetics to validate pharmacological targets
2 16 English
Lipoprotein metabolism
2 16 English
June
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Molecular Pharmacology and Applied Statistic 2 14 English
July
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Stem cells in experimental and clinical pharmacology 2 14 English