Molecular and Cellular Biology

Dottorati
Doctoral programme (PhD)
A.Y. 2020/2021
Study area
Science and Technology
Doctoral programme (PhD)
3
Years
Dipartimento di Bioscienze - Via Celoria, 26 - Milano
English
PhD Coordinator
The doctoral programme aims to:
- train scientific experts with excellent skills in the field of biomolecular sciences and biotechnology;
- promote a molecular approach to the study of complex biological problems in model organisms (prokaryotic and eukaryotic microorganisms, animals and plants);
- encourage collaboration between research institutes, advanced training schools and companies in the fields of biomolecular sciences and biotechnology;
- encourage internationalisation by promoting international scientific collaborations, involving foreign lecturers, recruiting postgraduate students from abroad, and organising co-tutored dissertations involving study periods abroad.
Training activities will be characterised by:
- a multidisciplinary approach;
- interactivity;
- links to the business world;
- internationalisation.
A key element of the programme is the direct involvement of doctoral students in experimental research activities. Students will work full-time on a research project, providing critical insight and suggestions, and thereby acquiring scientific and organisational independence.
Classi di laurea - Classes of master's degrees:

LM-6 Biologia,
LM-7 Biotecnologie agrarie,
LM-8 Biotecnologie industriali,
LM-9 Biotecnologie mediche, veterinarie e farmaceutiche,
LM-11 Conservazione e restauro dei beni culturali,
LM-13 Farmacia e farmacia industriale,
LM-17 Fisica,
LM-18 Informatica,
LM-21 Ingegneria biomedica,
LM-22 Ingegneria chimica,
LM-25 Ingegneria dell'automazione,
LM-31 Ingegneria gestionale,
LM-32 Ingegneria informatica,
LM-35 Ingegneria per l'ambiente e il territorio,
LM-40 Matematica,
LM-41 Medicina e chirurgia,
LM-42 Medicina veterinaria,
LM-44 Modellistica matematico-fisica per l'ingegneria,
LM-46 Odontoiatria e protesi dentaria,
LM-47 Organizzazione e gestione dei servizi per lo sport e le attività motorie,
LM-48 Pianificazione territoriale urbanistica e ambientale,
LM-51 Psicologia,
LM-52 Relazioni internazionali,
LM-53 Scienza e ingegneria dei materiali,
LM-54 Scienze chimiche,
LM-56 Scienze dell'economia,
LM-58 Scienze dell'universo,
LM-59 Scienze della comunicazione pubblica, d'impresa e pubblicità,
LM-60 Scienze della natura,
LM-61 Scienze della nutrizione umana,
LM-67 Scienze e tecniche delle attività motorie preventive e adattate,
LM-68 Scienze e tecniche dello sport,
LM-69 Scienze e tecnologie agrarie,
LM-70 Scienze e tecnologie alimentari,
LM-71 Scienze e tecnologie della chimica industriale,
LM-73 Scienze e tecnologie forestali ed ambientali,
LM-74 Scienze e tecnologie geologiche,
LM-75 Scienze e tecnologie per l'ambiente e il territorio,
LM-76 Scienze economiche per l'ambiente e la cultura,
LM-78 Scienze filosofiche,
LM-79 Scienze geofisiche,
LM-82 Scienze statistiche,
LM-86 Scienze zootecniche e tecnologie animali,
LM-91 Tecniche e metodi per la società dell'informazione,
LM-92 Teorie della comunicazione,
LM/SNT1 Scienze infermieristiche e ostetriche,
LM/SNT2 Scienze riabilitative delle professioni sanitarie,
LM/SNT3 Scienze delle professioni sanitarie tecniche,
LM/SNT4 Scienze delle professioni sanitarie della prevenzione
Dipartimento di Bioscienze - Via Celoria, 26 - Milano
Title Professor(s)
From protein structure to novel therapeutics against rare genetic diseases
Metabolic characterization of the immune response and cancer
Immunoregulation in the tumor microenvironment
Transposon Landscape Variation and its Influence on Phenotype Diversity in Plants
A. Bombarely
Characterisation of MIZ1-ECA1 interaction to shed light on the mechanisms underlying long-distance Ca2+ signalling in plants
Integrating pathogen genomes and health big data for challenging health-associated infections
Regulation of microtubules and RNA metabolism interaction in the neuron-astrocyte crosstalk during Parkinson’s disease
Computational design of enhanced antigens
In vivo modelling of liver cancer to resolve the chromatin dependencies of intestinal dysbiosis
M. Cassano
Genome editing of Transcription factors and cancer development
Implementing stem cell derived human neurons for studies on the pathogenesis and treatment of Huntington’s Disease
Unveiling the AIEC-antigens and gut-microbiota species involved in modulation of pathogenic Th1/17 cells differentiation and activation in Crohn’s disease
Molecular and genetic control of plant reproduction and seed development
Development and application of bioinformatics methods for large scale comparative genomics. Integration of multiple omics data for precision medicine approaches
Harnessing the new emerging imaging technologies to uncover the role of Ca2+ signaling in plant nutrient homeostasis
Bioinformatic Identification of key transcription factors in epithelial tumors
Defining the molecular and cellular mechanisms by which tissue macrophages promote angiogenesis in neovascular diseases
Molecular control of plant reproductive development in response to day length
Envelope biogenesis in Gram-negative bacteria as molecular target for the development of next generation antibacterial drugs
Study of the molecular mechanisms underlying the genesis and control of the cardiac rhythm in physiological and pathological conditions
Functional Analysis of Genes Controlling Inflorescence Architecture in Arabidopsis and Rice
Role of c-di-GMP and other nucleotide-derived signal molecules in Crohn’s disease-associated host-bacteria interaction
A zebrafish model to unravel the molecular bases of SOD1-mediated ALS pathogenesis
Study of the antiproliferative effect of metformin combined to transcranial stimulation in glioblastoma cellular and animal models
Development of genetic and pharmacological approaches to cure Muscular Dystrophies
Structure-function studies on ion channel proteins
Structural architecture of the “pioneer” transcription factor NF-Y and its companions on DNA
BarPLUS: improving photosynthesis in barley to increase the production of biomass that can be converted into biofuel
Envelope biogenesis in Gram-negative bacteria as molecular target for the development of next generation antibacterial drugs
Anthocyanin Mechanisms of cardioprotection
C. Tonelli
Dissecting the structural and biophysical bases of “cardiotoxicity” in Light Chain Amyloidosis
Regulators of Notch signaling in tumor biology
Development and implementationn of bioinformatic tools and workflows for cloud environments
Study of the functional and molecular mechanisms of familial cardiac pathologies using human and murine pluripotent stem cells
The response to DNA damage in non-proliferating cells: mechanisms and pathologies
Identification and characterization of new factors involved in maintaining genome stability
Identification of seed molecular regulators to develop new generation hybrids in agriculture
Insights into the role of DNA break processing factors in maintaining genome stability to target cancer cells
Structural characterization (X-ray, cryo EM) and functional analyses of protein-based nanotubules as antigen-presentation systems and adjuvants of the immune response
Stress-response signal integration by Transcription Factors interactions

Courses list

January 2021
Courses or activities Professor(s) ECTS Total hours Language
Optional
Biostatistics for Molecular and Cellular Biology
5 27 English
February 2021
Courses or activities Professor(s) ECTS Total hours Language
Compulsory
Molecular and Cellular Biology. Methods and Communication of Results
4 24 English
May 2021
Courses or activities Professor(s) ECTS Total hours Language
Optional
Scientific Visualization of Molecular Processes in the Cellular Environment
2 12 English
June 2021
Courses or activities Professor(s) ECTS Total hours Language
Optional
Introduction to the Analysis of Genome
6 30 English
September 2021
Courses or activities Professor(s) ECTS Total hours Language
Optional
How to Write a Molecular and Cellular Paper
4 20 English
Modern Imaging Techniques in Biology
2 14 English