The objectives of the course are to provide students with the most important notions related to the knowledge of the basic principles and fundamentals of nanotechnology and applications to inorganic and organic materials.
Goal The objectives of the course are to provide students with the most important notions related to the knowledge of the basic principles and fundamentals of nanotechnology and applications to inorganic and organic materials.
Course content Part I Basic concepts on the nanoparticles, their physico-chemical properties and how these latter can be modulated changing nano particles size will be presented In particular, the synthetic procedures using bottom-up approaches, for the preparation of different nanoparticle classes (metallic, semiconductors and quantum dots) will be described. The peculiar properties of the different types of nanoparticles (absorption, emission, modulation of the nanosized semiconductors band gap etc.) will be described. The most relevant strategies for nanoparticles stabilization in colloidal suspension, for the choice of the capping material as a function of the use of the nano-object, will be presented, as well as the techniques most commonly employed for their characterization in the solid state and in suspension. Some recent applications will be discussed. Moreover students will partecipate to a peculiar lesson on the use of databases in order to learn how to performe a literature search. TOTAL 24 h.
Part II Basic principles of superparamagnetic nanoparticles are illustrated: in particular, definitions, characteristics and potential applications are presented. In detail, iron oxide nanoparticles, such as maghemite and magnetite are discussed in terms of magnetic characteristics, synthesis and stabilization methods. The most important methods of functionalization of nanoparticles surface with organic molecules and biomolecules are presented. Basic principles of biomedical applications are also described: 1] in diagnostics, through the use of nanoparticles as contrast agents for magnetic resonance imaging and 2] in therapy, thanks to their ability to give hyperthermia, drug transport, vector fo cells uptake. TOTAL 24h
Reference material for students Students are given a file containing all of the slides presented during the course.
Requirement and examination procedure The examination will consist in an oral test for the Part I (Daniela Maggioni) and in a written test for the Part II of the course (Emanuela Licandro). The written test is composed of four questions mainly related to synthetic methodologies, discussed during the course, to conjugate superparamagnetic nanoparticles to organic molecules and biomolecules.
Requested background General Chemistry and Organic Chemistry I.
More info Students are expected to attend all of the lessons.