Industrial processes and scale-up

A.Y. 2018/2019
Lesson for
6
Max ECTS
48
Overall hours
SSD
CHIM/04
Language
English
Learning objectives
The main objective of the course is to emphasize the importance of scale-up methodology for the unit operations in chemical plants (reaction and separation processes), to give the theoretical basis for a correct approach to a scaling-up and to introduce the simulation science and the process simulation. The correct theoretical and experimental approaches of this kind of study will be presented and discussed; different industrial examples will be considered. Moreover, devoted software (PRO II) available to industrial chemists and engineers for the scaling-up operations will be presented and used in the course.

Course structure and Syllabus

Active edition
Yes
Responsible
CHIM/04 - INDUSTRIAL CHEMISTRY - University credits: 6
Lessons: 48 hours
Professor: Pirola Carlo
Syllabus
Course goals
The main objective of the course is to emphasize the importance of scale-up methodology for the unit operations in chemical plants (reaction and separation processes), to give the theoretical basis for a correct approach to a scaling-up and to introduce the simulation science and the process simulation. The correct theoretical and experimental approaches of this kind of study will be presented and discussed; different industrial examples will be considered. Moreover, devoted software (PRO II) available to industrial chemists and engineers for the scaling-up operations will be presented and used in the course.

Course content
The course will be devoted to a specific introduction of the scaling-up methodology for chemical processes from a chemical and an engineering point of view. Both chemical reactions and separation processes will be taken into account. More in detail, the following topics will be explained and discussed:

- Scaling-up of a chemical operation: meaning and importance
- Laboratories and pilot-plant studies
- Models for the interpretation of experimental data and simulation of a chemical unit operations: steady-state and dynamic models
- Physical and chemicals models
- Pilot plants: raw materials, mock-ups, degree of freedom, constructive materials, test program and use of results
- Experimental techniques in scaling-up methodology
- Applications to industrial process development: industrial examples and case-histories
- Control technology in chemical processes
- Environmental and regulatory issues
- Use of simulation softwares in the scaling-up: PRO II. Tutorial of these programs and their use for several aspects involved in the topics of the course.


Suggested prerequisites
Physical chemistry industrial, Chemical plants with lab, Physical chemistry I

Reference material
- A. C. Dimian, C. S. Bildea, A. A. Kiss: Integrated Design and Simulation of Chemical Processes", 2nd Edition, Elsevier (available in our Biblioteca di Chimica)
- V. Ragaini, C. Pirola, "Processi di Separazione nell'Industria Chimica", Hoepli
- The properties of Gases and Liquids Autori: B. Poling; J. 'O Connell; J. Prausnitz. McGraw-Hill 2004
- Scale-up Methodology for Chemical Process. Autori: J. B. Euzen, P. Trambouze, J. P. Wauquier, Edition Technip.
- All necessary materials will be made available during the course


Assessment method
Oral examination: All the topics considered in the course will be discussed in a oral examination. Theoretical questions and/or practical exercises using the simulation software will be requested.

Attendance
Strongly suggested

Type of course
traditional

Website
http://cpirolaicl.ariel.ctu.unimi.it/v3/Home/default.aspx

Other information
Altre informazioni: During the course, a visit in the Radici plant in Novara will be proposed and organized.
Lesson period
First semester
Lesson period
First semester
Assessment methods
Esame
Assessment result
voto verbalizzato in trentesimi
Educational website(s)
Professor(s)
Reception:
Monday: 9:30-13:30 am
Pilot Plants Laboratory (Build # 7 of the Chemistry Departement)