Biomarkers in animal models

A.Y. 2018/2019
Lesson for
8
Max ECTS
48
Overall hours
SSD
AGR/18 AGR/19 VET/05
Language
English
Learning objectives
The course addresses methods and techniques that are used in biomarkers defining and validation in different fields

Course structure and Syllabus

Active edition
Yes
Responsible
Biomarkers in animal nutrition
AGR/18 - ANIMAL NUTRITION AND FEEDING - University credits: 3
Lessons: 18 hours
Diagnostic tools in animal infectious diseases
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 3
Lessons: 18 hours
Laboratory techniques to test DNA-damage in animal models
AGR/19 - ANIMAL SCIENCE - University credits: 2
Lessons: 12 hours
ATTENDING STUDENTS
Diagnostic tools in animal infectious diseases
Syllabus
Aim of these lessons is description of the main bacterial, fungal and viral infectious diseases and the tools for the identification of causative agents
Laboratory techniques to test DNA-damage in animal models
Syllabus
Lectures
Causes and occurrence of oxidative stress damage (3 hours).
Evaluation of total anti-oxidant capacity and repairing mechanisms (2 hours).
Application of biomarkers for the screening and monitoring of oxidative status (2 hours)
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA (3 hours).
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems (2 hours).
Biomarkers in animal nutrition
Syllabus
Aim of the course:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status of an essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
lectures (16h)

Nutritional behavior
Nutritional status evaluation
Micronutrient status biomarkers

Practice training (16h)
Laboratory activities
Journal club

Final examination
A seminar on a specific topic related to the course contents

Books
·Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press
NON-ATTENDING STUDENTS
Diagnostic tools in animal infectious diseases
Syllabus
This course is only for frequenting students
Laboratory techniques to test DNA-damage in animal models
Syllabus
Lectures
Causes and occurrence of oxidative stress damage (3 hours).
Evaluation of total anti-oxidant capacity and repairing mechanisms (2 hours).
Application of biomarkers for the screening and monitoring of oxidative status (2 hours)
Development of DNA adducts, DNA repair pathways and assessment of oxidized bases in cellular DNA (3 hours).
Identification of valid and reliable biomarkers in monitoring oxidative status in biological systems (2 hours).
Biomarkers in animal nutrition
Syllabus
Aim of the course:
the course addresses the use of biomarkers of nutritional exposure and nutritional status. Different type of biochemical and functional index of status of an essential nutrient or other dietary constituents will be studied. The goal is to critically evaluate the state of the science of biomarkes of nutritional intake in animal models.

COURSE ORGANIZATION :
lectures (16h)

Nutritional behavior
Nutritional status evaluation
Micronutrient status biomarkers

Further knowledge
Methods in nutritional biomarkers evaluation
Principles of NMR


Final examination
A seminar on a specific topic related to the course contents

Books
· Biomarkers of nutritional exposure and nutritional status. J.Nutrition 2003 Vol 133. 3S demies Press
Lesson period
Second semester
Lesson period
Second semester
Assessment methods
Esame
Assessment result
voto verbalizzato in trentesimi