Grazioso Giovanni

Associate Professor
SSD
CHIM/08 - PHARMACEUTICAL CHEMISTRY
Competition sector
03/D1 - MEDICINAL, TOXICOLOGICAL AND NUTRITIONAL CHEMISTRY AND APPLIED TECHNOLOGIES

Contacts

Workplace

Via Mangiagalli, 25
20133 MILANO (MI)

Office phone number
02503 19352
Additional phone numbers
0250319351
University email address
Office hours
Friday 10.30 -12.30, fixing an appointment by email
Office
Office 2015 - Lab. 2053 - Via Mangiagalli 25

Teaching

Research

Publications
  • Isonitrile-Based Multicomponent Synthesis of β-Amino Boronic Acids as β-Lactamase Inhibitors / E. Bassini, S. Gazzotti, F. Sannio, L.L. Presti, J. Sgrignani, J. Docquier, G. Grazioso, A. Silvani. - In: ANTIBIOTICS. - ISSN 2079-6382. - 9:5(2020 May 12).
  • How computational chemistry and drug delivery techniques can support the development of new anticancer drugs / M. Garofalo, G. Grazioso, A. Cavalli, J. Sgrignani. - In: MOLECULES. - ISSN 1420-3049. - 25:7(2020 Apr 10), pp. 1756.1-1756.22.
  • Exploring Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Autoproteolysis Process by Molecular Simulations: Hints for Drug Design / J. Sgrignani, E.M.A. Fassi, C. Lammi, G. Roda, G. Grazioso. - In: CHEMMEDCHEM. - ISSN 1860-7179. - (2020). [Epub ahead of print]
  • Computationally Driven Structure Optimization, Synthesis, and Biological Evaluation of Imidazole-Based Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Inhibitors / C. Lammi, J. Sgrignani, A. Arnoldi, G. Lesma, C. Spatti, A. Silvani, G. Grazioso. - In: JOURNAL OF MEDICINAL CHEMISTRY. - ISSN 0022-2623. - 62:13(2019 Jun 18), pp. 6163-6174.
  • Rational design of allosteric modulators of the aromatase enzyme: An unprecedented therapeutic strategy to fight breast cancer / A. Spinello, S. Martini, F. Berti, M. Pennati, M. Pavlin, J. Sgrignani, G. Grazioso, G. Colombo, N. Zaffaroni, A. Magistrato. - In: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. - ISSN 0223-5234. - 168(2019 Apr 15), pp. 253-262.