Vaccinology

A.A. 2017/2018
Insegnamento per
8
Crediti massimi
48
Ore totali
SSD
AGR/18 VET/05
Lingua
Inglese
Obiettivi formativi
The course aims to provide a comprehensive and integrated overview in the important field of vaccinology, from immunology to all types of vaccine development, production, delivery and effect evaluation.

Struttura insegnamento e programma

Edizione attiva
Responsabile
Moduli o unità didattiche
Module: Innovative vaccine development and production
VET/05 - MALATTIE INFETTIVE DEGLI ANIMALI DOMESTICI - CFU: 3
Lezioni: 18 ore
Docente: Turin Lauretta

Module: Plant-based production of oral vaccines
AGR/18 - NUTRIZIONE E ALIMENTAZIONE ANIMALE - CFU: 2
Lezioni: 12 ore
Docente: Baldi Antonella

Module: Practical aspects of vaccinology
VET/05 - MALATTIE INFETTIVE DEGLI ANIMALI DOMESTICI - CFU: 3
Lezioni: 18 ore

STUDENTI FREQUENTANTI
Prerequisiti e modalità di esame
Esame orale
Metodi didattici
Frontali ed esercitativi
Module: Innovative vaccine development and production
Programma
Ricombinant vaccines development strategies
Subunit vaccines and Adjuvants (including liposomes, ISCOMs and VLPs)
Live attenuated recombinant vaccines
Genetic vaccines (DNA and RNA)
Innovative approaches (CpG motifs, peptide vaccines and others)
Metodi didattici
Theoretical and practical classes
Materiale didattico e bibliografia
Handouts will be provided by the teacher
Module: Practical aspects of vaccinology
Programma
History, passive & active immunization.
Veterinary vaccine development: from idea to delivery; market, registration and pharmacovigilance
Types of veterinary vaccines: from traditional to modern drugs
Field application of human and veterinary vaccines, herd immunity
Vaccine side effects: truth & hoax
Metodi didattici
Theoretical and practical classes
Materiale didattico e bibliografia
Course handouts in Ariel and directly provided by the teacher
Module: Plant-based production of oral vaccines
Programma
Plant transformation tools: Agrobacterium-mediated (stable and transient) and biolistic approach (4 hours).
Biomass Production and evaluation of heterologous antigenic protein expression: the example of tobacco plants (4 hours)
An example of application: pigs fed a tobacco seed based oral vaccines (4 hours).
Metodi didattici
seminars and laboratory activity
Materiale didattico e bibliografia
slides and laboratory manual
STUDENTI NON FREQUENTANTI
Prerequisiti e modalità di esame
Esame orale
Module: Innovative vaccine development and production
Programma
Ricombinant vaccines development strategies
Subunit vaccines and Adjuvants (including liposomes, ISCOMs and VLPs)
Live attenuated recombinant vaccines
Genetic vaccines (DNA and RNA)
Innovative approaches (CpG motifs, peptide vaccines and others)
Materiale didattico e bibliografia
Handouts will be provided by the teacher
Module: Practical aspects of vaccinology
Programma
History, passive & active immunization.
Veterinary vaccine development: from idea to delivery; market, registration and pharmacovigilance
Types of veterinary vaccines: from traditional to modern drugs
Field application of human and veterinary vaccines, herd immunity
Vaccine side effects: truth & hoax
Materiale didattico e bibliografia
Course handouts in Ariel and directly provided by the teacher
Module: Plant-based production of oral vaccines
Programma
Plant transformation tools: Agrobacterium-mediated (stable and transient) and biolistic approach (4 hours).
Biomass Production and evaluation of heterologous antigenic protein expression: the example of tobacco plants (4 hours)
An example of application: pigs fed a tobacco seed based oral vaccines (4 hours).
Materiale didattico e bibliografia
slides and laboratory manual
Periodo
Secondo semestre
Periodo
Secondo semestre
Modalità di valutazione
Esame
Giudizio di valutazione
voto verbalizzato in trentesimi
Docente/i
Ricevimento:
Sede di Via Trentacoste, 2
Ricevimento:
Lunedi pomeriggio ore 14-18
Studio - Sezione di Microbiologia e Immunologia Veterinaria - Via Celoria 10 - Milano