Systems and Diseases Ii
A.Y. 2024/2025
Learning objectives
The course represents the synthesis of the notions acquired during the first 3 years and the basis for the subsequent detailed clinical studies the will be carried out during Medical and Specialized Clinics.
The objects are the following:
-to provide the student with the knowledge on the main diseases of Gastrointestinal, Endocrinological, Emathological and Immunoreumathological systems (in particular, etiology, pathophysiology and clinical manifestations)
-to give the main information on the genetics and pathological basis of the above-mentioned diseases
-to provide students with the preparatory tools (language, case history, medical examination) for a correct approach to the patient
-to provide with the main clinical, biochemical, instrumental investigations available to perform a correct diagnosis
The objects are the following:
-to provide the student with the knowledge on the main diseases of Gastrointestinal, Endocrinological, Emathological and Immunoreumathological systems (in particular, etiology, pathophysiology and clinical manifestations)
-to give the main information on the genetics and pathological basis of the above-mentioned diseases
-to provide students with the preparatory tools (language, case history, medical examination) for a correct approach to the patient
-to provide with the main clinical, biochemical, instrumental investigations available to perform a correct diagnosis
Expected learning outcomes
1)To know the pathophysiology of:
DIGESTIVE TRACT
Dysphagia, Dyspepsia, gastroesophageal reflux, chronic gastritis, ulcer
Abdominal distension, Gas, digestion problems, Malabsorption
Intestinale obstruction
Abdominal pain
Jaundice
Hepatic insufficiency, viral and toxic hepatitis, liver diseases such as hemochromatosis and Wilson disease, sclerosant cholangitis
Hepatic encephalopathy
Portal hypertension
Biliary lithiasis
Ascites
Constipation
Diarrhea
Gastrointestinal bleeding
Chronic inflammatory bowel diseases (Crohn disease and ulcerative rectocolitis).
ENDOCRINE - METABOLIC SYSTEM:
Feed-back mechanism and interaction with the other systems
Circadian rithms of hormone secretion. Hormones mechanisms of action
Pathogenetic mechanisms of endocrine disorders and of metabolic diseases: eccess and deficiency
Hormone resistance, bioactivity, alterations of hormone peripheral metabolism
Diseases of thyroid, parathyroids, adrenals, gonads, hypothalamus and pituirary
Metabolic syndrome, insulin resistance
Diabetes type 1&2, gestational diabetes, obesity, hyperuricemia
Monogenic diabetes and obesity
Diabetes complications
Bone metabolism and osteoporosis
Hormones and nutrition
BLOOD:
Differentiation and maturation of blood cells
Role of growth factors
Pathophysiology of the main diseases of blood and lymphohemopoietic organs
Lymphoproliferative and Mieloproliferative diseases
Polycythemia vera and secondary polycythemia
Essential thrombocythemia
IMMUNE SYSTEM:
1) Approach to immunodeficiencies
Approach to autoimmune diseases
Approach to allergic diseases, asthma, rhinitis
Inflammatory arthritis
Infectious and post-infectious arthritis
Microcrystalline arthritis
Diseases of the connective tissue
Systemic vasculitis
Bone diseases
Painful syndromes
2) To know how to define a disease, its epidemiology, etiology and pathophysiology, nosography, signs and symptoms; to interpret the pathophysiological causes of signs and symptoms, the biochemical data, the instrumental investigations. The genetics and pathological basis is also requested for certain diseases.
3) To know the indications and limitations of the main diagnostic approaches
DIGESTIVE TRACT
Dysphagia, Dyspepsia, gastroesophageal reflux, chronic gastritis, ulcer
Abdominal distension, Gas, digestion problems, Malabsorption
Intestinale obstruction
Abdominal pain
Jaundice
Hepatic insufficiency, viral and toxic hepatitis, liver diseases such as hemochromatosis and Wilson disease, sclerosant cholangitis
Hepatic encephalopathy
Portal hypertension
Biliary lithiasis
Ascites
Constipation
Diarrhea
Gastrointestinal bleeding
Chronic inflammatory bowel diseases (Crohn disease and ulcerative rectocolitis).
ENDOCRINE - METABOLIC SYSTEM:
Feed-back mechanism and interaction with the other systems
Circadian rithms of hormone secretion. Hormones mechanisms of action
Pathogenetic mechanisms of endocrine disorders and of metabolic diseases: eccess and deficiency
Hormone resistance, bioactivity, alterations of hormone peripheral metabolism
Diseases of thyroid, parathyroids, adrenals, gonads, hypothalamus and pituirary
Metabolic syndrome, insulin resistance
Diabetes type 1&2, gestational diabetes, obesity, hyperuricemia
Monogenic diabetes and obesity
Diabetes complications
Bone metabolism and osteoporosis
Hormones and nutrition
BLOOD:
Differentiation and maturation of blood cells
Role of growth factors
Pathophysiology of the main diseases of blood and lymphohemopoietic organs
Lymphoproliferative and Mieloproliferative diseases
Polycythemia vera and secondary polycythemia
Essential thrombocythemia
IMMUNE SYSTEM:
1) Approach to immunodeficiencies
Approach to autoimmune diseases
Approach to allergic diseases, asthma, rhinitis
Inflammatory arthritis
Infectious and post-infectious arthritis
Microcrystalline arthritis
Diseases of the connective tissue
Systemic vasculitis
Bone diseases
Painful syndromes
2) To know how to define a disease, its epidemiology, etiology and pathophysiology, nosography, signs and symptoms; to interpret the pathophysiological causes of signs and symptoms, the biochemical data, the instrumental investigations. The genetics and pathological basis is also requested for certain diseases.
3) To know the indications and limitations of the main diagnostic approaches
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Linea Policlinico
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
Shifts:
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Lessons: 24 hours
: 12 hours
Informal teaching: 16 hours
: 12 hours
Informal teaching: 16 hours
Professors:
Mantovani Giovanna, Muller Ilaria
Shifts:
Gruppo 1
Professor:
Mantovani GiovannaGruppo 2
Professor:
Mantovani GiovannaGruppo 3
Professor:
Muller Ilaria
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
Shifts:
Gruppo 1
Professor:
Vecchi MaurizioGruppo 2
Professor:
Lampertico PietroGruppo 3
Professor:
Caprioli Flavio AndreaGruppo 4
Professor:
Tontini Gian Eugenio
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Shifts:
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Professor:
Bellocchi Chiara
Shifts:
Turno
Professor:
Bellocchi Chiara
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
: 4 hours
Lessons: 20 hours
Lessons: 20 hours
Professor:
Ghezzi Daniele
Shifts:
Turno
Professor:
Ghezzi Daniele
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 20 hours
: 4 hours
: 4 hours
Professor:
Bosari Silvano
Shifts:
Turno
Professor:
Bosari Silvano
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 20 hours
: 4 hours
Lessons: 20 hours
: 4 hours
Professors:
Chighizola Cecilia Beatrice, Favalli Ennio Giulio
Shifts:
Linea San Donato
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
Professors:
Finazzi Maria Chiara, Lussana Federico, Rambaldi Alessandro
Shifts:
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Lessons: 24 hours
: 12 hours
Informal teaching: 16 hours
: 12 hours
Informal teaching: 16 hours
Shifts:
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
Professor:
Vecchi Maurizio
Shifts:
Turno
Professor:
Vecchi Maurizio
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Professor:
Asti Emanuele Luigi Giuseppe
Shifts:
Turno
Professor:
Asti Emanuele Luigi Giuseppe
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Professors:
Proietti Marco, Zanichelli Andrea
Shifts:
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
: 4 hours
Lessons: 20 hours
Lessons: 20 hours
Professor:
Alcalay Myriam
Shifts:
Turno
Professor:
Alcalay Myriam
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 20 hours
: 4 hours
: 4 hours
Professor:
Pruneri Giancarlo
Shifts:
Turno
Professor:
Pruneri Giancarlo
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 20 hours
: 4 hours
Lessons: 20 hours
: 4 hours
Professors:
Gerosa Maria, Ingegnoli Francesca Anna
Shifts:
Linea San Giuseppe
Blood diseases
MED/15 - BLOOD DISEASES - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
Endocrinology
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 4
Lessons: 24 hours
: 12 hours
Informal teaching: 16 hours
: 12 hours
Informal teaching: 16 hours
Gastroenterology
MED/12 - GASTROENTEROLOGY - University credits: 4
Informal teaching: 16 hours
Lessons: 24 hours
: 12 hours
Lessons: 24 hours
: 12 hours
General surgery
MED/18 - GENERAL SURGERY - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Internal Medicine
MED/09 - INTERNAL MEDICINE - University credits: 1
Lessons: 8 hours
: 4 hours
: 4 hours
Professor:
Bellocchi Chiara
Medical genetics
MED/03 - MEDICAL GENETICS - University credits: 2
: 4 hours
Lessons: 20 hours
Lessons: 20 hours
Professor:
Tabano Silvia Maria
Pathology
MED/08 - PATHOLOGY - University credits: 2
Lessons: 20 hours
: 4 hours
: 4 hours
Professors:
Pelosi Giuseppe, Vago Gianluca Gaetano
Rheumatology
MED/16 - RHEUMATOLOGY - University credits: 3
Informal teaching: 16 hours
Lessons: 20 hours
: 4 hours
Lessons: 20 hours
: 4 hours
Professor(s)
Reception:
by appointment arranged by e-mail
Padiglione Zonda - Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - second floor
Reception:
Thursday 12.00 am - 01.00 pm
IRCCS Istituto Auxologico, via Ariosto 9, Milan
Reception:
Wednesday, 16.00-18.00 (only by appointment to be made by email)
ASST Gaetano Pini-CTO, Piazza Cardinal Ferrari 1, 20122 Milano
Reception:
by telephone appointment
via L. Temolo 4, 20126 Milano - Lab of Neurogenetics and mitochondrial disorders
Reception:
send me an email to meet me
Reception:
Monday 12.00-13.00 (by appointment)
Interhospital Pathology Division, Science and Technology Park, Via Fantoli 16/15, 20138 Milano