Basic Sciences
A.Y. 2026/2027
Learning objectives
The aim of this course is:
Know the fundamentals of chemistry necessary for the understanding of living matter and organic compounds of interest for biochemistry;
Know the molecular and biochemical mechanisms that underlie the vital processes and related metabolic activities;
Know the fundamental concepts of physics useful for understanding and interpreting physiological phenomena;
Know the structure and functions of the eukaryotic cell; Know the mechanisms of transmission and expression of genetic information.
Know the fundamentals of chemistry necessary for the understanding of living matter and organic compounds of interest for biochemistry;
Know the molecular and biochemical mechanisms that underlie the vital processes and related metabolic activities;
Know the fundamental concepts of physics useful for understanding and interpreting physiological phenomena;
Know the structure and functions of the eukaryotic cell; Know the mechanisms of transmission and expression of genetic information.
Expected learning outcomes
At the end of the course the student:
- will learn the behavior of biologically active molecules, gaining the appreciation of the chemical transformations in the life processes;
- will expose and explain, in a simple but rigorous manner, the chemical and biochemical phenomena or processes that are the basis of life;
- will be able to describe the structure and functions of a cell, including cell-cell communication;
- will be able to explain the content of Mendelian laws, about the transmission of monogenic characters and will know the mechanisms of gene expression and of the transmission of genetic information;
-will be able to provide a physical description of some key physiological processes;
- will understand the connections between chemistry, physic and biology;
- will be able to do exercises based on the fundamental concepts of physics and metrology.
- will learn the behavior of biologically active molecules, gaining the appreciation of the chemical transformations in the life processes;
- will expose and explain, in a simple but rigorous manner, the chemical and biochemical phenomena or processes that are the basis of life;
- will be able to describe the structure and functions of a cell, including cell-cell communication;
- will be able to explain the content of Mendelian laws, about the transmission of monogenic characters and will know the mechanisms of gene expression and of the transmission of genetic information;
-will be able to provide a physical description of some key physiological processes;
- will understand the connections between chemistry, physic and biology;
- will be able to do exercises based on the fundamental concepts of physics and metrology.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Prerequisites for admission
There are no specific prerequisites other than those required for admission to the degree course.
Assessment methods and Criteria
The written test includes closed and / or open-ended questions.
Biochemistry
Course syllabus
Atomic structure: chemical bonds: ionic and covalent bonds.
Intermolecular bonding: van der Waals forces and hydrogen bond.
Water: structure and properties; weak interactions in aqueous systems.
Aqueous solutions: concentration of solutions; colligative properties; osmosis.
Chemical reactions: basic concepts; reactions and chemical equilibrium; catalysts; redox reactions.
Ionic equilibrium: equilibrium of water autoionization; pH; acids and bases; buffer solutions.
Bonding in carbon compounds: common classes of organic compounds.
Biomolecules and their structures.
Enzymes: structure, regulation and mechanism of action.
Metabolism: overview of metabolism; anabolic and catabolic pathways.
Energy metabolism: high energy molecules; ATP cycle; mechanisms of ATP synthesis; Krebs cycle; electron transport chain and oxidative phosphorylation.
Carbohydrate metabolism, basic concepts: digestion; origin and metabolic pathways of glucose; regulation of carbohydrate metabolism.
Lipid metabolism, basic concepts: digestion; origin and metabolic pathways of fatty acids; regulation of lipid metabolism.
Amino acids metabolism, basic concepts: digestion; origin and metabolic pathways of amino acids; regulation of amino acids metabolism.
Proteins: primary, secondary, tertiary and quaternary structure. Hemoglobin.
Intermolecular bonding: van der Waals forces and hydrogen bond.
Water: structure and properties; weak interactions in aqueous systems.
Aqueous solutions: concentration of solutions; colligative properties; osmosis.
Chemical reactions: basic concepts; reactions and chemical equilibrium; catalysts; redox reactions.
Ionic equilibrium: equilibrium of water autoionization; pH; acids and bases; buffer solutions.
Bonding in carbon compounds: common classes of organic compounds.
Biomolecules and their structures.
Enzymes: structure, regulation and mechanism of action.
Metabolism: overview of metabolism; anabolic and catabolic pathways.
Energy metabolism: high energy molecules; ATP cycle; mechanisms of ATP synthesis; Krebs cycle; electron transport chain and oxidative phosphorylation.
Carbohydrate metabolism, basic concepts: digestion; origin and metabolic pathways of glucose; regulation of carbohydrate metabolism.
Lipid metabolism, basic concepts: digestion; origin and metabolic pathways of fatty acids; regulation of lipid metabolism.
Amino acids metabolism, basic concepts: digestion; origin and metabolic pathways of amino acids; regulation of amino acids metabolism.
Proteins: primary, secondary, tertiary and quaternary structure. Hemoglobin.
Teaching methods
Frontal lesson
Teaching Resources
Samaja M, Paroni R. Chimica e Biochimica per le lauree triennali dell'area Biomedica. Padova: Piccin,2017
Experimental biology
Course syllabus
Characteristics of the living matter: the cell theory; Methods to study the cell; Prokaryotes and eukaryotes; Levels of organization in Biology; Bases of biological evolution
Biological Macromolecules: Lipids, carbohydrates, nucleic acids and proteins.
Structure and organization of the eukaryotic cell: cellular compartmentalization; intracellular organelles; ribosomes; cytoskeleton; intercellular junction and extracellular matrix.
Structure and function of biological membranes: Fluid mosaic and transport across membranes
Cell-cell communications: How cells communicate with each other.
Cell cycle and cell-cycle regulation: Phases and control; cell death and transformation
Reproduction in living organisms: Sexual and asexual reproduction; mitosis and meiosis; gametogenesis, fertilization and differentiation.
DNA replication: the central dogma of molecular biology; DNA duplication and repair.
Transcription: Different types of RNA, RNA synthesis and maturation
Genetic code and protein translation: properties of the genetic code; protein synthesis and maturation.
The eukaryotic genome: chromatin structure; gene structure and control of gene expression.
Viruses: classification, structure and interaction with the host.
The Mendelian Laws and the transmission of monogenic traits: Genotype and phenotype; dominant, co-dominant and recessive alleles.
Monogenic genetic disease transmission: Cystic fibrosis; Thalassemia
Blood groups and multiple alleles
Biological Macromolecules: Lipids, carbohydrates, nucleic acids and proteins.
Structure and organization of the eukaryotic cell: cellular compartmentalization; intracellular organelles; ribosomes; cytoskeleton; intercellular junction and extracellular matrix.
Structure and function of biological membranes: Fluid mosaic and transport across membranes
Cell-cell communications: How cells communicate with each other.
Cell cycle and cell-cycle regulation: Phases and control; cell death and transformation
Reproduction in living organisms: Sexual and asexual reproduction; mitosis and meiosis; gametogenesis, fertilization and differentiation.
DNA replication: the central dogma of molecular biology; DNA duplication and repair.
Transcription: Different types of RNA, RNA synthesis and maturation
Genetic code and protein translation: properties of the genetic code; protein synthesis and maturation.
The eukaryotic genome: chromatin structure; gene structure and control of gene expression.
Viruses: classification, structure and interaction with the host.
The Mendelian Laws and the transmission of monogenic traits: Genotype and phenotype; dominant, co-dominant and recessive alleles.
Monogenic genetic disease transmission: Cystic fibrosis; Thalassemia
Blood groups and multiple alleles
Teaching methods
Frontal lesson
Teaching Resources
Chiricozzi E. et al. Elementi di Chimica e Biochimica. Napoli: Edises; 2022
Bonaldo P, Crisafulli C, D'Angelo R, Francolini M, Grimaudo S, Rinaldi C, Riva P, RomanelliMG. Elementi di biologia e genetica. Napoli: EdiSES 2019
Bonaldo P, Crisafulli C, D'Angelo R, Francolini M, Grimaudo S, Rinaldi C, Riva P, RomanelliMG. Elementi di biologia e genetica. Napoli: EdiSES 2019
Applied physics
Course syllabus
Introduction: Measurements in Physics. Fundamental and derived quantities. The International System of Units. Vector algebra.
Kinematics: Trajectory, displacement, velocity, acceleration, linear motion.
Dynamics - Newton's laws, gravitational force, force field, work, energy, power.
Statics - Equilibrium of a point particle, rigid body, torque, equilibrium of a rigid body, center of mass, stability, levers in the human body.
Statics e Dynamics of fluids - Aggregation states, density, pressure, Pascal's law, Stevin's law, Archimedes' principle, buoyancy, measurement of the pressure, flow rate, Hagen-Poiseuille's law.
Thermodynamics - Temperature, equation of state of an ideal gas, heat, specific heat, heat transfer.
Electrostatics and currents -Electric charge, Coulomb's law, potential energy and voltage, conductors and insulators, condenser, electrical current, Ohm's laws.
Radiations - Ionizing radiations, natural and artificial sources, radioactivity, radioactive decay, X ray.
Kinematics: Trajectory, displacement, velocity, acceleration, linear motion.
Dynamics - Newton's laws, gravitational force, force field, work, energy, power.
Statics - Equilibrium of a point particle, rigid body, torque, equilibrium of a rigid body, center of mass, stability, levers in the human body.
Statics e Dynamics of fluids - Aggregation states, density, pressure, Pascal's law, Stevin's law, Archimedes' principle, buoyancy, measurement of the pressure, flow rate, Hagen-Poiseuille's law.
Thermodynamics - Temperature, equation of state of an ideal gas, heat, specific heat, heat transfer.
Electrostatics and currents -Electric charge, Coulomb's law, potential energy and voltage, conductors and insulators, condenser, electrical current, Ohm's laws.
Radiations - Ionizing radiations, natural and artificial sources, radioactivity, radioactive decay, X ray.
Teaching methods
Frontal lesson
Teaching Resources
Borsa F, Lascialfari A, Principi di fisica. Napoli: Edises , 2020.
Contessa GM, Marzo GA. Fisica applicata alle scienze mediche. Bologna: Casa Editrice Ambrosianai, 2019
Contessa GM, Marzo GA. Fisica applicata alle scienze mediche. Bologna: Casa Editrice Ambrosianai, 2019
Modules or teaching units
Applied physics
PHYS-06/A - Physics for Life Sciences, Environment, and Cultural Heritage - University credits: 1
Lessons: 15 hours
Professor:
Spitaleri Andrea
Biochemistry
BIOS-07/A - Biochemistry - University credits: 2
Lessons: 30 hours
Professor:
Dei Cas Michele Vittorio
Experimental biology
BIOS-10/A - Cellular and Experimental Biology - University credits: 2
Lessons: 30 hours
Professor:
Rusconi Francesco Sebastiano
Professor(s)