Traslational cardiovascular medicine and surgery

A.A. 2021/2022
4
Crediti massimi
48
Ore totali
SSD
MED/11 MED/22 MED/23
Lingua
Inglese
Obiettivi formativi
The course takes the students into translational cardiovascular medicine and surgery starting with a disease-centered approach and ending with a patient-oriented approach of cardiovascular medicine and surgery.
It is designed in three blocks, each one presenting a main topic: cardiovascular diseases, vascular surgery and cardiac surgery.
Taking anatomy and epidemiology as starting point, the course focuses on the most important aspects of these pathologies examining risk factors, pathophysiological and clinical aspects. Special attention is given to the clinical presentation.
The course describes the main diagnostic and therapeutic procedures.
Risultati apprendimento attesi
Students are expected to :
- describe the severity of heart failure, evaluate the prognosis of the HF patient, recognise and describe the clinical role of HF comorbidities and principles of HF treatment.
- understand the indications for surgery in HF and the traditional surgical approaches and Describe the indications and eligibility for heart transplantation
- describe the epidemiology, pathophysiology, diagnosis and clinical features of arrhythmias and conduction disturbances
- discuss when a pacemaker is needed, describe the different types of pacemaker, cardiac defibrillators and cardiac resynchronization therapy
- describe the treatment of Coronary Artery Disease)
- describe the treatment Treatment of Pulmonary Artery Hypertention
- describe the treatment of myocardial infarction
- describe diagnosis and treatment of hypertrophic cardiomyopathy, infective endocarditis and fluid retention.
- describe the role of open surgery and endovascular stenting
- describe the actual role of open surgery and endovascular therapy
- describe the most recent indications for treatment and diagnostic tools of Aortic Diseases
- describe incidence, social impact and modern diagnosis and Conservative and advanced minimal invasive management of superficial and deep vein diseases
- describe the basics of cardiac surgery
- describe the indications for surgical therapy of Coronoary Artery Disease
- describe the clinical presentation of Aortic Valve Disease, the role of diagnostic workup in AVD, the current indications for AVD operation and post-surgical management
- describe the clinical presentation of Mitral and tricuspid valve disease, the role of diagnostic workup in MTVD, the current indications for MTVD operation and post-surgical management
- describe the indications for ascending aortic aneurysm operation and the rationale for valve sparing, the clinical presentation and diagnostic workup of acute aortic syndromes, the natural history of AAS and the indications for surgery
- describe transposition of the great arteries, tetralogy of Fallot, aortic coarctation
Programma e organizzazione didattica

Edizione unica

Responsabile
More specific information on the delivery modes of training activities for academic year 2021/22 will be provided over the coming months, based on the evolution of the public health situation.
Prerequisiti
To take the Translational Cardiovascular Medicine and Surgery exam, students must have already passed all the exams of the first and second year (Fundamentals of Basic Sciences, Cells, Molecules and Genes 1 and 2, Human Body, Functions and Mechanisms of Diseases).
Furthermore students must review in detail the program of System Diseases 1, in particular the modules of Cardiovascular Diseases and Diagnostic Imaging, and the programs of Pharmacology 1 and 2.
Modalità di verifica dell’apprendimento e criteri di valutazione
Students' evaluation will be assessed with oral examinations focused on the topics developed during the course.
Cardiovascular diseases
Programma
MODULE: CARDIOVASCULAR DISEASES
Lecture 1 - HF prognosis (2h)
Capability to define the severity of heart failure
Being able to evaluate the prognosis of the heart failure patient
Lecture 2 - HF comorbidities (2h)
Discussing the pathophysiology of lung-heart interactions
Discussing the clinical role of heart failure comorbidities
Lecture 3 - HF treatment (5h)
Acute HF treatment (1h)
Understanding of the role of exercise training programs in HF patients (1h)
Understand the complications of HF (1h)
Understanding the therapeutic approach of HF (1h)
Left ventricular assist device (LVAD) (1h)
Lecture 4 - Prevention of sudden death and treatment of arrhythmias (2h)
Understanding the epidemiology, pathophysiology, diagnosis and clinical features of arrhythmias and conduction disturbances
Understanding of the classification and definition of bradycardias, tachycardias, supraventricular arrhythmias (including atrial fibrillation and flutter) and ventricular arrhythmias
Lecture 5 - Pacemakers (2h)
Discussing when a pacemaker is needed
Presenting different types of pacemaker
Cardiac defibrillators
Cardiac resynchronization therapy
Lecture 6 - Treatment of CAD (2h)
Medical treatment of CAD
Percutaneous treatment of CAD
Lecture 7 - Treatment of PAH (2h)
PAH classification
PAH assessment
PAH treatment
Lecture 8 - Treatment of myocardial infarction (2h)
Diagnosis of myocardial infarction
Treatment of myocardial infarction
Lecture 9 - Clinical cases (2h)
Understanding the clinical evaluation process starting from patients' complaints.
Lecture 10 - Hypertrophic cardiomyopathy (1h)
Diagnosis of hypertrophic cardiomyopathy
Treatment of hypertrophic cardiomyopathy
Lecture 11 - Infective endocarditis (1h) Lecture 12 - Fluid retention (1h)
Metodi didattici
Lectures, Clinical cases, Case studies and Laboratory skills.
Materiale di riferimento
Harrison's Principles of Internal Medicine, 20th Edition, McGraw Hill Higher Education, 2018
Goldman's Cecil Medicine, L. Goldman, A. I. Schafer, 25th ed., Elsevier, 2015
Making Sense of Exercise Texting, R. B. Schoene, H. T. Robertson, CRC Press, 2019
Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Single Volume, D. Mann, D. Zipes, P. Libby, R. Bonow, 10th ed., Saunders, 2015
Rutherfords' Vascular Surgery, 8th edition, Elsevier, 2014
Johns Hopkins Textbook of Cardiothoracic Surgery, 2nd Edition, McGraw Hill, 2014
Cardiac surgery
Programma
MODULE: CARDIAC SURGERY
Lecture 1 - Basics of cardiac surgery (2h)
Understanding the basics of cardiopulmonary bypass
Understanding the basics of cardiac surgery
Lecture 2 - Coronary surgery (2h)
Describing the indications for surgical therapy of CAD
Describing alternative and innovative techniques for CABG
Lecture 3 - Aortic valve disease (2h)
Describing the clinical presentation of AVD
Understanding the role of diagnostic workup in AVD
Describing the current indications for AVD operation management and post-surgical
Describing the alternative trans-catheter approaches for AVD and the role of Heart Team
Lecture 4 - Mitral and tricuspid valve disease (2h)
Describing the clinical presentation of MTVD
Understanding the role of diagnostic workup in MTVD
Describing the current indications for MTVD operation and post-surgical management
Describing the alternative trans-catheter approaches for MTVD and the role of Heart Team
Lecture 5 - Ascending aorta diseases and acute aortic syndromes (2h)
Describing the indications for ascending aortic aneurysm operation and the rationale for valve sparing
Describing the clinical presentation and diagnostic workup of AAS
Describing the natural history of AAS and the indications for surgery
Optional CHD: PDA, transposition of the great arteries, tetralogy of Fallot, aortic coarctation
Lecture 6 - Heart Failure surgery and transplantation (2h)
Understanding the indications for surgery in HF and the traditional surgical approaches
Describing the rationale for mechanical support (e.g. ECMO and VAD implantation)
Describing the indications and eligibility for heart transplantation
Metodi didattici
Lectures, Clinical cases, Case studies and Laboratory skills.
Materiale di riferimento
Harrison's Principles of Internal Medicine, 20th Edition, McGraw Hill Higher Education, 2018
Goldman's Cecil Medicine, L. Goldman, A. I. Schafer, 25th ed., Elsevier, 2015
Making Sense of Exercise Texting, R. B. Schoene, H. T. Robertson, CRC Press, 2019
Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Single Volume, D. Mann, D. Zipes, P. Libby, R. Bonow, 10th ed., Saunders, 2015
Rutherfords' Vascular Surgery, 8th edition, Elsevier, 2014
Johns Hopkins Textbook of Cardiothoracic Surgery, 2nd Edition, McGraw Hill, 2014
Vascular surgery
Programma
MODULE: VASCULAR SURGERY
Lecture 1 - Carotid artery disease (3h, Nano)
Discussing indication for symptomatic and asymptomatic patients
Role of open surgery and endovascular stenting
Lecture 2 - Lower extremity artery disease (3h, Nano)
Understanding diabetic and atherosclerosis lesions
Describing the actual role of open surgery and endovascular therapy
Lecture 3 - Thoracic and Abdominal Aortic Diseases (3h, Trimarchi)
Understanding the most recent indications for treatment and diagnostic tools
Debating on therapeutic management of aortic diseases
Lecture 4 - Superficial and deep vein diseases (3h, Trimarchi)
Understanding incidence, social impact and modern diagnosis
Conservative and advanced minimal invasive management
Metodi didattici
Lectures, Clinical cases, Case studies and Laboratory skills.
Materiale di riferimento
Harrison's Principles of Internal Medicine, 20th Edition, McGraw Hill Higher Education, 2018
Goldman's Cecil Medicine, L. Goldman, A. I. Schafer, 25th ed., Elsevier, 2015
Making Sense of Exercise Texting, R. B. Schoene, H. T. Robertson, CRC Press, 2019
Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, Single Volume, D. Mann, D. Zipes, P. Libby, R. Bonow, 10th ed., Saunders, 2015
Rutherfords' Vascular Surgery, 8th edition, Elsevier, 2014
Johns Hopkins Textbook of Cardiothoracic Surgery, 2nd Edition, McGraw Hill, 2014
Moduli o unità didattiche
Cardiac surgery
MED/23 - CHIRURGIA CARDIACA - CFU: 1
Lezioni: 12 ore

Cardiovascular diseases
MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE - CFU: 2
Lezioni: 24 ore

Vascular surgery
MED/22 - CHIRURGIA VASCOLARE - CFU: 1
Lezioni: 12 ore

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Ricevimento:
Lunedi ore 13.00 - 15.00; Giovedì ore 11.00 - 13.00
Fondazione IRCCS Cà Granda Ospedale Policlinico Milano - Pad. Zonda