Communicable and non-communicable diseases

A.A. 2023/2024
8
Crediti massimi
64
Ore totali
SSD
BIO/19 MED/04
Lingua
Inglese
Obiettivi formativi
The objective of the course is to provide a specific knowledge and a critical evaluation on the pathological bases for precision medicine interventions. The overall learning objective is thus to provide an updated discussion of selected topics on precision medicine, which is notoriously a present and future important biomedical approach and includes relevant biotechnological aspects. The course includes two modules: Pathological bases for precision medicine interventions and Infectious diseases and drug resistance. In the first module, the following topics will be discussed: general principles of precision medicine, molecular determinants of individual health, precision medicine in oncology (molecular determinants, examples of precision medicine in oncology), precision medicine in cardiovascular and metabolic health, machine learning and artificial intelligence for precision medicine. In the second module, the following topics will be discussed: overview of human-microbe interactions, antimicrobial compounds: mechanism of action and resistance, identifying novel conventional targets for antimicrobial discovery, and non-conventional targets for novel generation of antimicrobial compounds, challenges in novel antimicrobial compound discovery.
Risultati apprendimento attesi
At the end of the course, the students are expected to possess a solid knowledge and understanding on the pathological bases for precision medicine interventions. The acquired skills and competencies will be the tools through which the students will improve their capacity to correlate the different concepts in different areas of precision medicine, applying their skills to the comprehension of complex problems in this field. Moreover, they will be enabled to implement better judgment, communication skills and learning abilities in this complex scientific area, especially in relationship with topics relevant to biotechnology.
Corso singolo

Questo insegnamento può essere seguito come corso singolo.

Programma e organizzazione didattica

Edizione unica

Responsabile
Periodo
Primo semestre

Programma
The course includes two modules: Pathological bases for precision medicine interventions and Infectious diseases and drug resistance.
In the first module, the following topics will be discussed: a) atherosclerotic cardiovascular diseases; b) hypertension; c) metabolic syndrome; d) diabetes; e) genetic determinant of non-alcoholic fatty liver disease; f) immunity (innate and acquired); g) extracellular vescicles.
In the second module, the following topics will be discussed: overview of human-microbe interactions, antimicrobial compounds: mechanism of action and resistance, identifying novel conventional targets for antimicrobial discovery, and non-conventional targets for novel generation of antimicrobial compounds, challenges in novel antimicrobial compounds discovery.
Prerequisiti
Conoscenze di base di anatomia, fisiologia, biochimica e microbiologia.
Metodi didattici
Lezioni frontali
Materiale di riferimento
Verranno forniti agli studenti articoli specifici sugli argomenti trattati nel corso
Diapositive del corso sul sito Ariel
Libri suggeriti:
a) Pathological bases for precision medicine interventions (Robbins and Cotran).
b) Authors : Abul K. Abbas & Andrew H. Lichtman & Shiv Pillai; Cellular and Molecular Immunology, 10th Edition.
Modalità di verifica dell’apprendimento e criteri di valutazione
Per il primo modulo (Prof. Ruscica) è previsto l'esame orale. La valutazione è espressa in trentesimi.
Moduli o unità didattiche
Infectious diseases and drug resistance
BIO/19 - MICROBIOLOGIA
MED/04 - PATOLOGIA GENERALE
Lezioni: 16 ore

Pathological bases for precision medicine interventions
BIO/19 - MICROBIOLOGIA
MED/04 - PATOLOGIA GENERALE
Lezioni: 48 ore

Docente/i
Ricevimento:
Su appuntamento
INGM, via Francesco Sforza 35 o DiSFeB, via Balzaretti 9, Milano
Ricevimento:
su appuntamento
Dipartimento di Scienze Farmacologiche e Biomolecolari - Via Balzaretti 9 - Milano
Ricevimento:
previo appuntamento via e-mail
Dipartimento di Scienze Farmacologiche e Biomolecolari (DISFeB), Via Balzaretti 9