Protein biochemistry

The aim of the Protein Biochemistry course is to explore, at an advanced level, the structural and functional features that support the many and various activities of proteins in the cell. The course will cover the theoretical bases of protein structure, activity and dynamics, with examples from diseases related to protein misfolding and dysfunction, and molecular medicine. For different topics, research approaches employed for the advanced study of protein biochemistry and function will be analyzed and discussed.

By the end of the course, students will have achieved a proficient, in-depth understanding of molecular mechanisms that underlie the main cellular processes, linked to protein synthesis, turnover, proteotoxicity and regulation. The students will therefore acquire the cultural tools for understanding the structural bases of physiological and pathological protein functions, and for the critical and applied analysis of protein biochemistry at the molecular and cellular levels.