Structural Biology of the Cell

Principles regulating actin filament (AFs) and microtubule (MTs) dynamics. Specific roles of AFs and MTs in plant cells with respect to the animal cells. The MT dynamics as the major determinant of the cell wall structure and the plant cell shape. Protein complexes involved in MT nucleation (model of dispersed MTOcs) and MT dynamics in isodiametrically and tip growing cells (3CFU).
Cell Biology in the scientific lab. Imaging technology and the cytoskeleton. Structure and relevance of the cytoskeleton in disease and diagnostics. Unconventional signaling through cellular shape. (1C.F.U). Disease and target-oriented cell biology. Functional analysis of gene function by cell biology (data discussion). (1C.F.U). The "Professor corner": ribosomes and translation in the regulation of gene expression, growth and differentiation (1C.F.U)
Material
Slides; texts to be defined; articles in Ariel web site; scientific literature

Prerequisites and Exam Modalities
Good knowledge of biology. Willing to participate to discussions. Basic knowledge of plant cell biology. Written examinations (Moscatelli). Written plus oral examination (Biffo).

Counseled propedeutics
Biochemistry. Molecular biology.

Teaching methods
Interactive lessons. Frontal lectures. Attendance is preferred.

Teaching language
English

Information on coursework
Ariel and other sites will be available with further explanations and articles.
The lectures will be provided to the students