Histology
A.Y. 2019/2020
Learning objectives
The course addresses cell morphology and ultrastructure, tissue organization of human cells and tissues, as well as the main methods and the instruments for their morphological analysis. Morphological and structural aspects of cell and tissues are described and discussed in relation to their functional role.
The core of knowledge acquired during this course is fundamental to understand the human anatomy, and functions and pathologies of the different organs and systems.
At the end of the course the student should be able to:
· Describe and identify tissues and cell ultrastructure
· Possess sufficient knowledge to proficiently attend the subsequent courses.
The core of knowledge acquired during this course is fundamental to understand the human anatomy, and functions and pathologies of the different organs and systems.
At the end of the course the student should be able to:
· Describe and identify tissues and cell ultrastructure
· Possess sufficient knowledge to proficiently attend the subsequent courses.
Expected learning outcomes
Recognize and describe eukariotic cells and their ultrastructure, the structure of human tissues and their localization in the human body, and the functional aspects in relation to the morphological organization.
Describe the mechanisms responsible for gametogenesis, fertilization, and the early stages of embryonic development, and the key characteristics of embryo annexes.
Describe the mechanisms responsible for gametogenesis, fertilization, and the early stages of embryonic development, and the key characteristics of embryo annexes.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Course syllabus
CYTOLOGY and HISTOLOGY:
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes. Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation
1st and 2nd week of embryo development
3rd week of embryo development
Embryo annexes
Introduction to histology. Instruments and methods for samples preparation and observation at the microscope.
Cell membrane and inner cell compartments (endoplasmic reticulum, Golgi apparatus), ribosomes.
Vesicle trafficking. Exocytosis and endocytosis. Lysosomes. Peroxisomes. Mitochondria.
Cytoskeleton.
Nucleus, nucleolus, cell cycle.
Epithelia: apical and basolateral specializations of epithelial cells. Cell junctions.
Lining epithelia: classification and localizations.
Exocrine glands.
Endocrine glands.
Connective tissue: cellular components and extracellular matrix.
Connective tissue: proper connective tissue. Adipose tissue.
Cartilage.
Bone and osteogenesis.
Blood and hemopoiesis.
Muscle tissue: skeletal, cardiac and smooth muscle tissues.
Nervous tissue
Dental tissues.
EMBRYOLOGY:
Male gametogenesis. Testes and cycle of the seminiferous epithelium. Introduction to genital ducts.
Female gametogenesis. Ovary and uterus. Maturation of follicles and menstrual cycle
Fertilization. Early stages of the embryo development. Segmentation. Morula. Blastocyst implantation
1st and 2nd week of embryo development
3rd week of embryo development
Embryo annexes
Prerequisites for admission
There are no specific pre-requirements for the Histology and Embryology course.
Teaching methods
Teaching methods (all compulsory):
· Lectures
· Tutorial activities at the light microscope
Attendance required.
· Lectures
· Tutorial activities at the light microscope
Attendance required.
Teaching Resources
Histology
Rosati, Colombo, Maraldi. Istologia - Edi Ermes.
Adamo et al. Istologia di Monesi - Piccin.
Maraldi, Tacchetti et al. Istologia medica - Edi-Ermes.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embryology
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Atlas
Wheater. Istologia e anatomia microscopica - Masson.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Dalle Donne, Gagliano et al. Istologia ed elementi di anatomia microscopica - Edises.
Useful bibliography
Gagliano. QuickReviews Istologia - Edises.
Rosati, Colombo, Maraldi. Istologia - Edi Ermes.
Adamo et al. Istologia di Monesi - Piccin.
Maraldi, Tacchetti et al. Istologia medica - Edi-Ermes.
Ross, Pawlina. Istologia: testo e atlante - Casa Editrice Ambrosiana.
Embryology
Barbieri, Carinci. Embriologia - Casa Editrice Ambrosiana.
De Felici et al. Embriologia umana - Piccin.
Atlas
Wheater. Istologia e anatomia microscopica - Masson.
Ross, Pawlina, Barnash. Atlante di istologia e anatomia microscopica - Casa Editrice Ambrosiana.
Dalle Donne, Gagliano et al. Istologia ed elementi di anatomia microscopica - Edises.
Useful bibliography
Gagliano. QuickReviews Istologia - Edises.
Assessment methods and Criteria
the assessment method includes a written test and an oral exam; it is mandatory to pass the written test for the admission at the oral exam;
- the written test is a multiple choice test including 40 questions in 75 minutes; each question has 5 possible answers;
- the oral exam consists in the observation, description and identification of histological samples on micrographs and in a discussion on the topics included in the course program.
- assessment parameters: the knowledge of histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- assessment: final mark (/30) based on the results of all tests;
- communication of results: the results of the written test will be published on the Ariel website.
-Mark: the final mark will be obtained according to the performance of the oral examination. The mark will not be the average of the written test, but the performance level may positively improve the mark of the oral examination.
The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
- the written test is a multiple choice test including 40 questions in 75 minutes; each question has 5 possible answers;
- the oral exam consists in the observation, description and identification of histological samples on micrographs and in a discussion on the topics included in the course program.
- assessment parameters: the knowledge of histology and embryology, the ability to recognize and describe tissues based on the specific microscopic characteristics, and the efficacious communication of the information and with the appropriate terms will be assessed.
- assessment: final mark (/30) based on the results of all tests;
- communication of results: the results of the written test will be published on the Ariel website.
-Mark: the final mark will be obtained according to the performance of the oral examination. The mark will not be the average of the written test, but the performance level may positively improve the mark of the oral examination.
The exam is deemed to be passed successfully if the final grade is equal to or higher than 18/30.
Registration to exams through SIFA is mandatory for each session.
BIO/17 - HISTOLOGY - University credits: 7
: 10 hours
Informal teaching: 16 hours
Lessons: 62 hours
Informal teaching: 16 hours
Lessons: 62 hours
Professors:
Barni Luisa, Gagliano Nicoletta, Sartori Patrizia Mirella
Shifts:
-
Professor:
Gagliano NicolettaGruppo 1
Professors:
Barni Luisa, Sartori Patrizia MirellaGruppo 2
Professors:
Barni Luisa, Sartori Patrizia MirellaProfessor(s)