Neuromuscular physiology and endocrinology

A.Y. 2019/2020
Overall hours
BIO/09 MED/13
Learning objectives
The course provides a broad overview of cell physiology, with particular attention to: excitable membranes, neuromuscular membranes, motor control, the endocrine system and relative organs, hormonal secretion, common congenital and acquired endocrine-metabolic diseases. The course gives an introduction to the use and interpretation of noninvasive methods for studying metabolism.
Expected learning outcomes
Students will acquire general knowledge of cell physiology, neuromuscular physiology, motor control, and the endocrine system, knowledge in identifying the anatomy and function of endocrine organs and their activity in health and illness; the role that individual organs and tissues play in nutrient metabolism in normal conditions, during fasting, prolonged fasting, postprandial period, during acute exercise, and after training.
Course syllabus and organization

Single session

Lesson period
Second semester
Course syllabus
Neuromuscular Physiology Module (42 hours)
o Body fluids and hydrosaline balance: The water compartments, Composition of body fluids, Exchanges between compartments, Hydrosaline balance.
o General neurophysiology: Biophysics of excitable membranes; Ionic channels; Membrane potentials; Conduction of membrane potentials, classification of nerve fibers and synaptic transmission, receptors, spinal reflexes.
Muscle physiology: General information on skeletal muscle tissue, Organization of skeletal muscle tissue, Contraction mechanism, Muscle energy, Neuromuscular synapse and excitation-contraction coupling, Types of contraction, Muscle performance, Muscle fatigue, Influence of joint movement on performance, Pathways of transmission of force.
o Elements of functional anatomy and organization of the central nervous system: Organization of the central nervous system and its levels of integration, Principles of functioning of the central nervous system, Methods of investigation of the central nervous system.
o Vegetative nervous system: Elements of functional anatomy, Sympathetic nervous system, Parasympathetic nervous system, Synaptic transmission of the vegetative nervous system, Control of the vegetative nervous system, Vegetative nervous system and effector organs
o Somatic sensitivity and pain: Principles of sensory physiology, nervous mechanisms of somatic sensitivity, pretalamic mechanisms, thalamo-cortical mechanisms, pain, descending control of sensitivity and pain.
o Motor control: Relationship between perception and action, Integration of sensory information with motor commands, Organization of voluntary movement, Cortical organization of movement, Control of muscle tone and posture, Cerebellum, Nuclei from the base.
o Integrative central nervous system functions: Exercise and brain, Associative areas and superior functions of the cortex.
Prerequisites for admission
Elements of neuro- and muscle-skeletal anatomy
Teaching methods
Teaching Resources
Fisiologia dell'uomo, AAVV, Edi-Ermes;
Attività Fisica: Fisiologia, adattamenti all'esercizio, prevenzione, sport-terapia e nutrizione, AAVV, Ed. Poletti.
Assessment methods and Criteria
Twenty multiple choice questions.
BIO/09 - PHYSIOLOGY - University credits: 6
MED/13 - ENDOCRINOLOGY AND METABOLISM - University credits: 3
Lessons: 63 hours
Professors: Ce' Emiliano, Luzi Livio
Monday and Friday, from 9.00 to 17.00
Via Giuseppe Colombo 71, 2nd Building, mezzanine floor ; via Skype: emiliano_ce; via Teams: