This course aims at providing the student with the knowledge required to tackle all the fundamental problems of organic chemistry, with particular emphasis on the study of the chemical properties and reactivity of aliphatic compounds.
Expected learning outcomes
The student will acquire a good understanding of structure and reactivity of aliphatic organic molecules; he/she will be able to describe reaction mechanisms and to predict on their basis the course of unknown reactions; they will be able to formulate synthetic strategies for molecules of low complexity.
This course aims at providing the student with the knowledge required to tackle all the fundamental problems of organic chemistry, with particular emphasis focussed on the study and the understanding of the chemical properties and reactivity of aliphatic compounds. In the theory part of the course the concepts of chemical bonding and atom ibridization will be briefly summarized, followed by an introduction to stereochemistry and conformational analysis (10 hours). Then, the standard classification of organic compounds on the basis of their reactivity deriving from the presence of functional groups will be presented in the following sequence: alkanes, haloalkanes, alcohols, thiols, amines, alkenes, alkynes, polyenes, allylic and other delocalized systems (12 hours). Carbonyl compounds and their reactivity (10 hours). Carboxylic acids and their derivatives (12 hours). Retrosynthetic analysis (4 hours).
With the in-class exercises (16 hours) the student will be trained in solving simple problems of organic chemistry and of retro-synthetic analysis of relatively complex structures.
Prerequisites for admission
Basic knowledge of general and inorganic chemistry
Traditional - In class execises - On line exercises Attendance: recommended
Brown, Foote, Iverson, Anslyn: Organic Chemistry V Ed., Thomson Learning, Inc., Glendale, CA, USA.
Assessment methods and Criteria
Written and oral examination: the written text will include problems related to all the topics discussed in the course (15 questions, the student should reach the evaluation of 18/33); after passing the written exam, the student will take an oral examination that involves the discussion on the synthesis of an organic molecule on the blackboard and, possibly, some questions on the theory (reaction mechanisms, characteristics and properties of organic molecules and reagents).