Pharmacology 1 and Pharmacology 2
A.Y. 2019/2020
Learning objectives
Understand the cellular and molecular basics of pharmacology
- Provide adequate knowledge on the major drugs classes, both small molecules and biologicals.
- Provide adequate knowledge on the major drugs classes, both small molecules and biologicals.
Expected learning outcomes
Knowledge and understanding of the main fundamentals of pharmacology, including pharmacodynamics, drug safety and toxicity
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
year
Course syllabus
Pharmacology 1
Introduction to pharmacology. Receptors: main aspects of receptor function. Metabotropic G-coupled receptors, receptor operated channels (ROC), tyrosine kinase receptors, intracellular receptors. Signal transduction, post-translational modifications (sumoylation, phosphorylation). Voltage Operated channels (VOC), adhesion molecules. General pharmacology: drugs and pharmacological targets, agonists, antagonists, drug potency and efficacy, drug-receptor interactions. Main neurotransmitter systems: glutamatergic system, cholinergic system, GABAergic system.
Pharmacology 2
Dopamine and drugs for Parkinson's Disease; drugs for Alzheimer's Disease; anti-epileptic drugs; hypnotic drugs; drugs for depression; drugs for multiple sclerosis. Biotechnological drugs: therapeutic use, differences with small molecules. Steroidal and nonsteroidal anti inflammatory drugs. Drugs for hypertension; drugs for asthma. Anti-cancer drugs; drugs for diabetes; drugs for rheumatoid arthritis; drugs for migraine. Pharmacokinetic and drug-interactions.
Introduction to pharmacology. Receptors: main aspects of receptor function. Metabotropic G-coupled receptors, receptor operated channels (ROC), tyrosine kinase receptors, intracellular receptors. Signal transduction, post-translational modifications (sumoylation, phosphorylation). Voltage Operated channels (VOC), adhesion molecules. General pharmacology: drugs and pharmacological targets, agonists, antagonists, drug potency and efficacy, drug-receptor interactions. Main neurotransmitter systems: glutamatergic system, cholinergic system, GABAergic system.
Pharmacology 2
Dopamine and drugs for Parkinson's Disease; drugs for Alzheimer's Disease; anti-epileptic drugs; hypnotic drugs; drugs for depression; drugs for multiple sclerosis. Biotechnological drugs: therapeutic use, differences with small molecules. Steroidal and nonsteroidal anti inflammatory drugs. Drugs for hypertension; drugs for asthma. Anti-cancer drugs; drugs for diabetes; drugs for rheumatoid arthritis; drugs for migraine. Pharmacokinetic and drug-interactions.
Prerequisites for admission
Physiology and Pathology are two courses very useful for the understanding of the topics planned in Pharmacology 1-2
Teaching methods
Frontal teaching
Teaching Resources
General and Molecular Pharmacology: Principles of Drug Action - Clementi, Fumagalli, Wiley
Assessment methods and Criteria
Oral
Pharmacology 1
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Professor:
Gardoni Fabrizio
Shifts:
-
Professor:
Gardoni Fabrizio
Pharmacology 2
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Professor:
Gardoni Fabrizio
Shifts:
-
Professor:
Gardoni FabrizioProfessor(s)
Reception:
Monday 9.00 a.m.
Via Balzaretti 9, DiSFeB