Veterinary Microbiology and Immunology
A.Y. 2019/2020
Learning objectives
Acquisition of the basic knowledge of immunology with particular reference to the main differences in animal species. Acquisition of basic knowledge of biosecurity and veterinary microbiology with particular reference to the pathogenic activities of bacteria and virology. Furthermore the main microbiological and immunological techniques of classical and innovative diagnostics applied in veterinary will be presented. In addition, the course aims to improve the student's skills and critical analysis skills, providing the basis for an experimental design in the field of veterinary microbiology and immunology.
Expected learning outcomes
At the end of the course, the student must be aware of the immune system characteristics and of the most relevant specificities in different animal species, and be able to apply the main immunological tests used in veterinary medicine. The student must know the characteristics that condition the pathogenicity of microorganisms; moreover, and be able to apply and understand the results of microbiological diagnostic tests and the antibiogram. The student must also know the characteristics of the viruses and the main notions of biosecurity, as well as understand and realize a simple experimental protocol of microbiology and immunology.
Lesson period: Second semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Course syllabus
Veterinary immunology
Introduction: history of immunology and general information about the immune system
Innate immunity
- Pathogen recognition
- Inflammation mediators
- Neutrophils and phagocytosis
- Macrophages and the resolution of inflammation
- The systemic response to inflammation
- The complement
- Cytokines and cellular signaling
- NK cells
Adaptive immunity
- Antigens
- Dendritic cells and antigen presentation
- Lymphoid organs
- Lymphocytes
- T lymphocytes and antigen response
- B lymphocytes and humoral immunity
- The structure of antibodies
- The origin of antigen receptor diversity
- Cell-mediated immunity
The regulation of immunity
Local Immunity
Immunization and vaccines
The response to pathogens
Immunopathology
Immunodiagnostic techniques, generalities
Practical tutoring:
Laboratory immunodiagnostic techniques and disposable immunodiagnostic devices
Cytofluorimetry
Veterinary microbiology
Basic knowledge of Biosafety
- personal protective equipment and biohazard
- biosecurity on farms
Microorganisms as pathogens
- virus generality: morphology structure and genetics of viruses
- bacteriophages
- main viruses of veterinary interest
- stages of viral infection and interactions with the host cell
- unconventional infectious agents: prions
- pathogenicity factors
Microbiological diagnostics applied to veterinary public health
- main isolation and identification techniques
- main virological diagnostics techniques
Antibacterial and antiviral in veterinary
- physical and chemical systems for the control of microorganisms
- chemotherapy and antibiotics
- antimicrobial resistance
Practical tutoring:
Extraction and separation of bacterial or viral proteins from biological samples by molecular techniques
Evaluation of bacterial resistance from biological samples (e.g. milk)
Introduction: history of immunology and general information about the immune system
Innate immunity
- Pathogen recognition
- Inflammation mediators
- Neutrophils and phagocytosis
- Macrophages and the resolution of inflammation
- The systemic response to inflammation
- The complement
- Cytokines and cellular signaling
- NK cells
Adaptive immunity
- Antigens
- Dendritic cells and antigen presentation
- Lymphoid organs
- Lymphocytes
- T lymphocytes and antigen response
- B lymphocytes and humoral immunity
- The structure of antibodies
- The origin of antigen receptor diversity
- Cell-mediated immunity
The regulation of immunity
Local Immunity
Immunization and vaccines
The response to pathogens
Immunopathology
Immunodiagnostic techniques, generalities
Practical tutoring:
Laboratory immunodiagnostic techniques and disposable immunodiagnostic devices
Cytofluorimetry
Veterinary microbiology
Basic knowledge of Biosafety
- personal protective equipment and biohazard
- biosecurity on farms
Microorganisms as pathogens
- virus generality: morphology structure and genetics of viruses
- bacteriophages
- main viruses of veterinary interest
- stages of viral infection and interactions with the host cell
- unconventional infectious agents: prions
- pathogenicity factors
Microbiological diagnostics applied to veterinary public health
- main isolation and identification techniques
- main virological diagnostics techniques
Antibacterial and antiviral in veterinary
- physical and chemical systems for the control of microorganisms
- chemotherapy and antibiotics
- antimicrobial resistance
Practical tutoring:
Extraction and separation of bacterial or viral proteins from biological samples by molecular techniques
Evaluation of bacterial resistance from biological samples (e.g. milk)
Prerequisites for admission
Knowledge of cell biology and basic microbiology; basic chemistry and biochemistry skills
Teaching methods
Lectures and use of televoter and instant polling. Seminars and round tables; participation in thematic study days. Exercises in a single-place laboratory
Teaching Resources
Ian Tizard: Veterinary Immunology;
Giorgio Poli et al.: Veterinary Microbiology and Immunology ed. EDRA
Material (publications, presentations, diagrams and protocols) provided or indicated by the teacher
Immunology: contents deposited in the teacher's Ariel webpages
Giorgio Poli et al.: Veterinary Microbiology and Immunology ed. EDRA
Material (publications, presentations, diagrams and protocols) provided or indicated by the teacher
Immunology: contents deposited in the teacher's Ariel webpages
Assessment methods and Criteria
Multiple choice test; Oral examination with evaluation of experimental projects and discussion of the topics covered during the course.
Immunologia
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 4
Practicals: 8 hours
Single bench laboratory practical: 8 hours
Lessons: 24 hours
Single bench laboratory practical: 8 hours
Lessons: 24 hours
Professor:
Addis Maria Filippa
Shifts:
-
Professor:
Addis Maria Filippa
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VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 3
Single bench laboratory practical: 16 hours
Lessons: 16 hours
Lessons: 16 hours
Professor:
Soggiu Alessio
Shifts:
-
Professor:
Soggiu AlessioProfessor(s)