Clinical Pharmacology and Pharmacoepidemiology and Pharmacoeconomics

A.Y. 2020/2021
Overall hours
Learning objectives
The aim of the course is to present the students with the most important aspects of clinical and epidemiological evaluation of a drug. The main topics covered during the course will be the experimental, legislative, ethical, clinical, economical and pharmaco-epidemiological aspects of drug discovery and use.
Expected learning outcomes
At the end of the course, the student will be able to follow the entire development of a new active compound or pharmaceutical formulation, to understand how to design a clinical study needed for marketing the new drug, and how to evaluate the results of this study from the clinical, pharmacoeconomical and pharmacoepidemiological points of view.
Course syllabus and organization

Single session

Lesson period
Second semester
If the health authorities will not allow the presence of students in the classrooms, the lessons will be given via Microsoft Teams.
The final oral exam will be via Teams as well.
Prerequisites for admission
Students are required to attend and pass the exam of Pharmacology and Pharmacotherapy before attending the present course.
Assessment methods and Criteria
Oral exam covering all the topics of the course.
Clinical pharmacology
Course syllabus
1. How a drug is born
2. How to study a drug
3. Preclinical phase: innovation and the discovery of new drugs
4. Tissue cultures in drug development
5. Use of animal models and alternatives in drug development
6. Clinical phases: I, II, III, IV
7. Clinical experimentation: characterization of the diverse phases of a clinical study
8. Clinical protocol: how it is made
9. Experimental design
10. Special patients: the elderly, the young, the obese, the nephropathic, the hepatopatic
11. Anti-cancer chemotherapy
12. Vaccines
Teaching methods
Oral lessons and use of PCs for database consultation.
If necessary, lessons will be via Teams.
Teaching Resources
All the slides presented at the course and the recording of the lessons will be published on the Ariel web site.
Pharmacoepidemiology and Pharmacoeconomics
Course syllabus
1. Pharmacoeconomy
2. Pharmacoepidemiology
3. Meta-analysis
4. Pharmacoepigenomics
5. Pharmacogenomics
6. Pharmacovigilance
7. Appropriateness in prescribing
8. Generic drugs
9. How to search for medical info in the web and in the databases
10. Risk management.
Teaching methods
Oral lessons in normal classrooms.
If the health situation will require it (pandemic still ongoing), oral lessions via Microsoft Teams. When possible, lessons via Teams will be recorded.
Teaching Resources
All the slides presented at the course and the recordings of the lessons will be published on the Ariel web site.
Clinical pharmacology
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Pharmacoepidemiology and Pharmacoeconomics
BIO/14 - PHARMACOLOGY - University credits: 4
Lessons: 32 hours
Please, send an email to schedule an appointment
Office, second floor at the Department of Pharmacological and Biomolecular Sciences, via Balzaretti 9, Milan