Functional genomics

A.Y. 2020/2021
6
Max ECTS
48
Overall hours
SSD
BIO/18
Language
English
Learning objectives
Functional Genomics is the field of molecular biology that is involved with assigning function and interactions to genes and their products and ranges from the detailed study of individual genes (forward genetics), large scale experimental approaches designed to capture global effects and interactions. The course in Functional Genomics" provides participants with deep knowledge about the latest genome wide and single gene approaches to study gene functions in model organisms. Teaching is especially focused on helping students gain the expertise required to decide which approaches and technologies to use to investigate biological pathways and the function of genes involved in them.

The development of several high throughput analytical approaches in molecular biology has revolutionized genomics. In particular, Next Generation Sequencing has wide application to many functional genomics settings.
Expected learning outcomes
Undefined
Course syllabus and organization

Single session

Responsible
Lesson period
First semester
Lectures are provided via Ariel asynchronously by power point presentations with audio files. Regularly lessons (total 12 CFU) will take place via the Zoom platform to help and facilitate a better understanding of the lessons.

Evaluation will be through written exams (online) using the exam.net / SEB protocol and Zoom surveillance (see instruction manual on Ariel). The examination consists of 6 open questions of which the students will have to select 5 questions to answer.
The content and other considerations are all unchanged.
Course syllabus
Whole genome sequencing
Genome annotation
Gene family analysis
Reverse genetics strategies in prokaryotes and eukaryotes
Transcriptomics
Small non-coding RNA function and their analysis
Regulatory pathway analysis
Proteomics strategies
Protein interactions and complex formation
Protein analysis in living cells.
Prerequisites for admission
Learning assessment will be through a written exam at the end of the course. The examination will consist of 6 open questions during which, students must answer 5. Each question contributes equally to the final score.
Teaching methods
Frontal lectures. At the end of the course, there will be an additional question time during which students can ask for extra explanations regarding all the topics that were discussed during the lessons.
Teaching Resources
Scientific papers and reviews will be presented during lectures and all materials will be uploaded on the Ariel website, lecture attendance is strongly encouraged.
Assessment methods and Criteria
Learning assessment will be through a written exam at the end of the course. The examination will consist of 6 open questions of which, students must answer 5. Each question contributes equally to the final score.
BIO/18 - GENETICS - University credits: 6
Lectures: 48 hours