Toxicological Chemistry and Laboratory of Chemical and Toxicological Analysis

A.Y. 2020/2021

Max ECTS

Overall hours

SSD

CHIM/08

Language

Italian

Included in the following degree programmes

Pharmacy (Classe LM-13)-Enrolled from 2009/10 Academic Year

Learning objectives

The objective of the course is to study the link between the chemical structure and the toxicity of the molecules. The principal classes of substances of abuse will be considered as regard as their potential of abuse, the relative Italian legislation and their pharmacological action. The principal analytical methods for the detection of the drugs of abuse in both biological and non-biological samples will be taken into account, even by means of practical experiments in laboratory.

Expected learning outcomes

At the end of the course students will be able to know the potential of abuse of the most common drugs of abuse and the relative Italian legislation. Students will also be able to know the principal analytical and sample preparation techniques to be applied in the field of chemical and toxicological analysis.

Lesson period: First semester

Lessons timetable

Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi

Exams calendar

Single course

This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.

Search a single course

Course syllabus and organization

Linea Unica

Responsible

Roda Gabriella

Lesson period

First semester

Emergency remote teaching

Lessons will be held on the TEAMS platform, during the time scheduled and the registration will be available on the Ariel or teams platform.
Laboratory will be held in presence if possible.
The program is the same
Tha exam if possibile will be done in a clossroom if not on the teams platform

Syllabus

Prerequisites for admission

Students must have attended the previous courses and passed the preparatory exams

Assessment methods and Criteria

Written exam: four multiple choice tests, three chemical structures of substances treated during the course. One question about the experiments carried out in the laboratory. Three questions on the theoretical part.

Toxicological Chemistry

Course syllabus

History of toxicological chemistry. History of poisons and their definition and classification. Diagnosis of poisoning. Methods in chemical and toxicological investigation. Generic and specific investigation. Withdrawal and conservation of samples. Immunological screening. Aliphatic hydrocarbons, halogenated hydrocarbons, aromatic hydrocarbons. Sniffing.
Volatile anesthetics. Volatile organic poisons (CO, HCN) and their detection. Ethanol and its legislation related to driving. Methanol. Drugs of abuse. Legislation relative to drug dealing, detention and abuse. Opium, opiates, opioids. Cocaine. Cannabis. Psychostimulants. LSD, GHB. Psychoactive plants. Psychoactive mushrooms. Barbiturates. Benzodiazepines. Doping

Teaching methods

Frontal lessons

Teaching Resources

The slides of the course are on the ARIEL site

Laboratory of Chemical and Toxicological Analysis

Course syllabus

Generic investigation on plasma samples. Determination of ethanol in beverages. Determination of ethanol by microdiffusion. Extraction of methadone from a syrup and its determination by GC/FID. Extraction of nicotine from hair and its determination by GC/MS. Extraction of morphine from urine samples

Teaching methods

Practical exercitations in laboratory

Teaching Resources

Experimental procedures are on the ARIEL site and are given and explained in the preliminary lesson

Course structure

Laboratory of Chemical and Toxicological Analysis

CHIM/08 - PHARMACEUTICAL CHEMISTRY - University credits: 1

Single bench laboratory practical: 16 hours

Professor: Roda Gabriella

Shifts:

Turno 1

Professor: Roda Gabriella