Organic compounds are the basis for living organisms. This teaching will describe structure, physio-chemical properties and reactivity of the main classes of organic compounds, with particular emphasis for those important for environment.
Expected learning outcomes
At the end of the teaching the student will have acquired: - the capacity to understand the chemical structure and reactivity of organic compounds, and their environmental importance; - the knowledge of the main functional groups; - the knowledge of the fundamental techniques for the identification, separation and purification of organic compounds.
(CFU 1) he organic compounds: structure, isomerism, compact formula, functional group. Intermolecular bonds in the organic compounds and their relationship with chemical-physical proprieties: volatility, solubility, etc. Alkanes and cycloalkanes: conformational analysis; chemical-physical proprieties; radical reactions; radical's stability. Alkenes: structure, proprieties, geometric isomerism. Dienes and polyenes (short account). Addition reactions of alkenes: electrophilic and nucleophilic reagents. Radical reactions of alkenes. Alkanes and alkenes in nature: terpenes (short account). Aromatic compounds: some derivative of benzene, polycycles and heterocyclic aromatic compounds. nomenclature and structure of aromatic compounds. (CFU 2) Alkyl halides: structure, reactivity, proprieties and ecological problems. Alcohols: structure, proprieties, acidity and redox reactions. Phenols: structure, proprieties, acidity and redox reactions. Antioxidants. Other oxigenated derivatives: quinones ethers, epoxides. Organosulfur compounds compounds: thiols and disulfur derivatives. (CFU 3) Chirality and optical activity, absolute and relative configuration. Enantiomers, diasteroisomers and racemic mixtures. Relationship between biological proprieties and optical active compounds. CFC and ozone's hole. Aldehydes and ketones: structure, proprieties, redox and nucleophic addition reactions. Semiacetals, acetals and hydrated derivative of aldehydes and ketones. Some typical carbonyl addition reactions of nitrogen nucleophilic reagent. Carbohydrates: mono-, di- and polysaccharides. (CFU 4) Monosaccharides: structure and Fisher projections, stereochemistry. Cyclic structure and mutarotation. Disaccharides and polysaccharides: proprieties and importance in biological system. (CFU 5) Carboxylic acids: proprieties and reactions. Funcional derivatives of carboxilyc acids: acid halides, esters, amides, anhydrides, carbammates, uree. Reactions of nucleophilic displacements: esterifications and hydrolysis of esters and amides. Lipids: fatty acids, triglycerids, phospholipids. Soap and tensioactives. Amines: structure, proprieties, basicity. Natural nitrogen containing compounds (short account). Aminoacids and peptide bond, pI. Peptides and proteins. Exercises in preparation to the exam. (CFU 6) Laboratory.
Prerequisites for admission
Inorganic and General Chemistry
Lectures ( 5CFU) and practical laboratory activities (1CFU).
Course slides. Recommended texts: P. Y. Bruice, Elements of Organic Chemistry (Edises). Includes ebook version. W. Brown, T. Poon, Introduction to organic chemistry (Edises). Includes molecular models. F. S. Lee, Guide to solving problems from: W. Brown, T. Poon, Introduction to organic chemistry (Edises).
Assessment methods and Criteria
No intermediate tests. The exam consists of a one and a half hour written test (20 questions with a closed answer) and an oral exam (30 minutes) subject to passing the preceding test. 12 correct answers out of 20 mean the candidate has passed. The correct answers are worth 1 point, wrong answers or not given are worth 0 points. The test results will be communicated via the Ariel platform. During the oral examination the correctness of the candidate's language and of the chemical terms will be evaluated. Furthermore, the ability to link the various topics covered in the course will be evaluated. The vote will be out of 30. The test includes all the topics of the course plus those covered in the laboratory. Students with DSA certification are required to promptly notify the Teacher to agree with the methods of examination. Students enrolled in an exam session and no longer wishing to support it are required to unsubscribe.