Technology and Pharmaceutical Legislation and Toxicology Ii
A.Y. 2021/2022
Learning objectives
The aim of the course is to introduce the students to the main classes of xenobiotics (natural and synthetic molecules) exerting toxic effects on humans. Exposure conditions are examined, the toxic effects are described, and the molecular mechanisms explaining the toxicity of the different molecules are analyzed. Experimental and epidemiological data defining the risk assessment are critically analysed. Another objective of the course is that of providing knowledge of the legislation in the environmental and occupational health and safety fields for the protection of the environment, flora, fauna, ecosystems and human health from the impacts deriving from human activities. The knowledge of the prescriptions in this area represents a useful completion of the professional skills both for those who will work in companies that have to deal with these regulatory requirements, and for those who will work at environmental protection agency, at analysis laboratories or who will support the institutions in identifying new emission limits based on available technologies or discoveries about the toxic effects of the substances used in production processes.
Expected learning outcomes
At the end of the course the student must demonstrate to possess an adequate knowledge of the toxic effects of natural and synthetic molecules and of the mechanisms explaining their toxicity. The student is also expected to be able to critically analyse toxicological issues, based on the available data: experimental, occupational and epidemiological.
Expected learning outcomes also include: acquisition of the bases to understand environmental legislation and on Health and Safety; knowledge of the objectives and principles of the environmental legislation and on Health and Safety; knowledge of the main mandatory regulatory aspects applicable in companies, organizations, laboratories, and used by supervisory bodies in the control activities about environmental impacts and about the Health and Safety.
Expected learning outcomes also include: acquisition of the bases to understand environmental legislation and on Health and Safety; knowledge of the objectives and principles of the environmental legislation and on Health and Safety; knowledge of the main mandatory regulatory aspects applicable in companies, organizations, laboratories, and used by supervisory bodies in the control activities about environmental impacts and about the Health and Safety.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
year
More specific information on the delivery modes of training activities for academic year 2021/22 will be provided over the coming months, based on the evolution of the public health situation. During the emergency phase, the exams will be in oral form instead of written.
Prerequisites for admission
The students must have knowledge of general toxicology, organ toxicology and environmental toxicology. They must also have basic knowledge of wave and radiation physics and of generation and propagation of waves and radiation.
Assessment methods and Criteria
Toxicology 2 - The students are asked to write the answer to four open questions on the topics discussed during the course. A score expressed in thirtieths is given to each answer. The exam is passed if the students reach the score of 18/30 in three out of the four answers and the average score of the four answers is at least 18/30. To support the students, two partial tests are carried out during the course, on the first and the second half of the program, respectively. Each test consists of three open questions. A score expressed in thirtieths is given to each answer. Each test is passed if the students reach the score of 18/30 in two out of the three answers and the average score of the three answers is at least 18/30. The two tests are passed if the average score of the first and second test is at least 18/30.
The oral presentation given by the students during the training hours will also contribute, up to 5%, to the final mark.
Technology and pharmaceutical legislation - The students are asked to write the answer to six open questions on the topics discussed during the course. Each question has a score based on the complexity of the content and this score is indicated on the text. The sum of the scores is 30/30. The test is passed if the sum of the scores of the answers is at least 18/30. To facilitate students in studying and passing the exam, two partial tests are carried out during the course. Each test consists of three questions relating to the topics covered from the start of the course until the date of the test or from the lesson following the first test, until the last lesson of the course. Each question has a score as described above, but the sum of the scores is equal to 15/30. Only those who reach the score of at least 8/30 in the first test are allowed to take part in the second one. The two tests are passed if the sum of the scores of the first and second tests is at least 18/30.
The oral presentation given by the students during the training hours will also contribute, up to 5%, to the final mark.
Technology and pharmaceutical legislation - The students are asked to write the answer to six open questions on the topics discussed during the course. Each question has a score based on the complexity of the content and this score is indicated on the text. The sum of the scores is 30/30. The test is passed if the sum of the scores of the answers is at least 18/30. To facilitate students in studying and passing the exam, two partial tests are carried out during the course. Each test consists of three questions relating to the topics covered from the start of the course until the date of the test or from the lesson following the first test, until the last lesson of the course. Each question has a score as described above, but the sum of the scores is equal to 15/30. Only those who reach the score of at least 8/30 in the first test are allowed to take part in the second one. The two tests are passed if the sum of the scores of the first and second tests is at least 18/30.
Toxicology II
Course syllabus
Classroom teaching
Animal toxins: origin, toxic effects and mechanisms of toxicity
Toxic effects of plants and mechanisms of toxicity
Allergy to pollens and air pollution
Toxicological risk of herbal products and food supplements
Toxic effects of poisonous mushrooms
Toxic effects of pesticides
Toxic effects of metals
Toxic effects of solvents and vapors
Toxic effects of susbstance abuse
Doping in sports
Consequences of alcohol abuse
Consequences of sigarette smoking
Air, soil, water pollutants
Effects on human health of air pollution
Biomonitoring of the environment
Chemical and biological weapons
Forensic toxicology
Microbiota, xenobiotics and health
Prion disease: features, mechanisms and diffusion in the environment
Food packaging: toxicological risk
Cosmetics: toxicological risk
Endocrine disruptors and human health
Classroom training
The students will receive publications or indications of websites where to study specific topics of interest within the program of the course. Students will then give a short presentation on the selected topic. The training also includes a technical visit to a plant, which has to manage an important environmental impact.
Animal toxins: origin, toxic effects and mechanisms of toxicity
Toxic effects of plants and mechanisms of toxicity
Allergy to pollens and air pollution
Toxicological risk of herbal products and food supplements
Toxic effects of poisonous mushrooms
Toxic effects of pesticides
Toxic effects of metals
Toxic effects of solvents and vapors
Toxic effects of susbstance abuse
Doping in sports
Consequences of alcohol abuse
Consequences of sigarette smoking
Air, soil, water pollutants
Effects on human health of air pollution
Biomonitoring of the environment
Chemical and biological weapons
Forensic toxicology
Microbiota, xenobiotics and health
Prion disease: features, mechanisms and diffusion in the environment
Food packaging: toxicological risk
Cosmetics: toxicological risk
Endocrine disruptors and human health
Classroom training
The students will receive publications or indications of websites where to study specific topics of interest within the program of the course. Students will then give a short presentation on the selected topic. The training also includes a technical visit to a plant, which has to manage an important environmental impact.
Teaching methods
10 CFU: 8 CFU teaching and 2 CFU training, in attendance and using the Teams platform
Teaching Resources
The teacher provides power point files summarizing each lesson. The files have to be integrated with student's notes and scientific articles suggested by the teacher.
Reference text: Casarett & Doull's. Toxicology, McGraw-Hill.
Reference text: Casarett & Doull's. Toxicology, McGraw-Hill.
Technology and Pharmaceutical Legislation
Course syllabus
Environmental legislation: evolution of European and national environmental legislation. Objectives of the legislation, efficacy and effectiveness of the instruments introduced. Parallelism between environmental and health and safety legislation in terms of required fulfilments, responsibilities and sanctions. Environmental impact prevention tools and environmental authorizations: VIA, AIA, AUA.
Legislation for the protection of water bodies both from a quantitative and qualitative point of view, regulation of water discharges and circular economy of water resources; atmospheric emissions legislation and related authorizations. Regulation of emissions of smells.
Ionizing Radiation and Non-Ionizing Radiation: physical characteristics, effects on biological material and current legislation.
Noise: effects on humans, current legislation and related requirements for environmental protection and workers' health and safety.
European and national waste legislation: definitions, CER codes, reduction, reuse, recycling, waste-to-energy and final sink, company requirements: loading and unloading register, forms, temporary storage, producer responsibility, marine litter, package of circular economy for waste, European strategy for plastics.
General training of workers for health and safety according to the State Regions agreement of 21/12/2011 concerning: concepts of risk, damage, prevention, protection, organization of corporate prevention, rights, duties and sanctions for the various corporate subjects, bodies surveillance, control and assistance.
For the entire duration of the emergency phase, it will not be possible to organize any technical visit to a plant.
Legislation for the protection of water bodies both from a quantitative and qualitative point of view, regulation of water discharges and circular economy of water resources; atmospheric emissions legislation and related authorizations. Regulation of emissions of smells.
Ionizing Radiation and Non-Ionizing Radiation: physical characteristics, effects on biological material and current legislation.
Noise: effects on humans, current legislation and related requirements for environmental protection and workers' health and safety.
European and national waste legislation: definitions, CER codes, reduction, reuse, recycling, waste-to-energy and final sink, company requirements: loading and unloading register, forms, temporary storage, producer responsibility, marine litter, package of circular economy for waste, European strategy for plastics.
General training of workers for health and safety according to the State Regions agreement of 21/12/2011 concerning: concepts of risk, damage, prevention, protection, organization of corporate prevention, rights, duties and sanctions for the various corporate subjects, bodies surveillance, control and assistance.
For the entire duration of the emergency phase, it will not be possible to organize any technical visit to a plant.
Teaching methods
3 CFU teaching by web trough MS Teams
Teaching Resources
The teacher provides power point files which must be integrated with students' notes and scientific and legislative texts for any further information. The power point file was designed to be sufficiently complete and exhaustive even for a worker student who couldn't take part in the classroom lesson.
Technology and Pharmaceutical Legislation
CHIM/09 - PHARMACEUTICAL AND TECHNOLOGICAL APPLICATIONS OF CHEMISTRY - University credits: 3
Lessons: 24 hours
Professor:
Camera Marta
Toxicology II
BIO/14 - PHARMACOLOGY - University credits: 10
Practicals: 32 hours
Lessons: 64 hours
Lessons: 64 hours
Professor:
Chiesa Giulia Maria Carola
Professor(s)