Veterinary Microbiology and Immunology
A.Y. 2021/2022
Learning objectives
Acquisition of the basic knowledge of immunology with particular reference to the main differences in animal species. Acquisition of basic knowledge of biosecurity and veterinary microbiology with particular reference to the pathogenic activities of bacteria and virology. Furthermore the main microbiological and immunological techniques of classical and innovative diagnostics applied in veterinary will be presented. In addition, the course aims to improve the student's skills and critical analysis skills, providing the basis for an experimental design in the field of veterinary microbiology and immunology.
Expected learning outcomes
At the end of the course the student must know the characteristics of the immune system of the different animal species. He must know and be able to apply the main immunological tests used in veterinary medicine. He must know the characteristics that condition the pathogenicity of microorganisms; moreover he must know and be able to apply and understand the results of microbiological diagnostic tests and the antibiogram. He must know the characteristics of the viruses and the main notions of biosecurity. Understand and realize a simple experimental protocol of microbiology and immunology.
Lesson period: Second semester
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
Second semester
Specific indications will be provided based on the evolution of the COVID pandemics and related regulations
Course syllabus
Veterinary Immunology
Introduction: a brief history of Immunology and a general introduction to the immune system
Innate immunity
· The Recognition of Invaders
· Inflammation Mediators
· Neutrophils and Phagocytosis
· Macrophages and Recovery from Inflammation
· Systemic Responses to Inflammation
· The Complement System
· The Cytokines
· NK cells
Adaptive Immunity
· Antigens
· Dendritic Cells and Antigen Processing
· Organs of the Immune System
· Lymphocytes
· Helper T Cells and Their Response to Antigen
· B Cells and Their Response to Antigen
· Antibodies: structure and functions
· How Antigen-Binding Receptors Are Made
· Cell-mediated immunity
· Regulation of Adaptive Immunity
Immunity at Body Surfaces
Immunization and Vaccines
Immunity to Pathogens
Hypersensitivity and Autoimmunity: General Principles
Immunodiagnostic Techniques
Practicals: ELISA, Western Immunoblotting, Lateral flow devices, SNAP
Veterinary Microbiology
Biosafety
· Individual protection devices and biohazard
· Biosafety in animal farming
Microorganisms as pathogens
· Viruses: basic notions on morphology and functions
· Bacteriophages
· Main viruses of veterinary interest
· Stages of viral infection and interaction with the host cell
· Unconventional infectious agents: prions
· Pathogenicity factors
Microbiological diagnosis applied to public health
· Main isolation and identification techniques
· Main techniques for virological diagnosis
Antibacterials and antiseptics in the veterinary sector
· Physical and chemical systems for microorganism control
· Chamioterapics and antibiotics
· Antimicrobial resistance
Practicals:
Extraction and separation of bacterial or viral proteins from biological samples by means of molecular techniques
Evaluation of the bacterial resistome in biological samples (eg. Milk)
Introduction: a brief history of Immunology and a general introduction to the immune system
Innate immunity
· The Recognition of Invaders
· Inflammation Mediators
· Neutrophils and Phagocytosis
· Macrophages and Recovery from Inflammation
· Systemic Responses to Inflammation
· The Complement System
· The Cytokines
· NK cells
Adaptive Immunity
· Antigens
· Dendritic Cells and Antigen Processing
· Organs of the Immune System
· Lymphocytes
· Helper T Cells and Their Response to Antigen
· B Cells and Their Response to Antigen
· Antibodies: structure and functions
· How Antigen-Binding Receptors Are Made
· Cell-mediated immunity
· Regulation of Adaptive Immunity
Immunity at Body Surfaces
Immunization and Vaccines
Immunity to Pathogens
Hypersensitivity and Autoimmunity: General Principles
Immunodiagnostic Techniques
Practicals: ELISA, Western Immunoblotting, Lateral flow devices, SNAP
Veterinary Microbiology
Biosafety
· Individual protection devices and biohazard
· Biosafety in animal farming
Microorganisms as pathogens
· Viruses: basic notions on morphology and functions
· Bacteriophages
· Main viruses of veterinary interest
· Stages of viral infection and interaction with the host cell
· Unconventional infectious agents: prions
· Pathogenicity factors
Microbiological diagnosis applied to public health
· Main isolation and identification techniques
· Main techniques for virological diagnosis
Antibacterials and antiseptics in the veterinary sector
· Physical and chemical systems for microorganism control
· Chamioterapics and antibiotics
· Antimicrobial resistance
Practicals:
Extraction and separation of bacterial or viral proteins from biological samples by means of molecular techniques
Evaluation of the bacterial resistome in biological samples (eg. Milk)
Prerequisites for admission
Basic knowledge of cellular biology and basic microbiology; basic knowledge of chemistry and biochemistry.
Teaching methods
Class lectures integrated with instant polling (es. Kahoot, Slido) for enhancing student participation. Practical content lectures. Laboratory activities.
Teaching Resources
Ian Tizard: Veterinary Immunology;
Giorgio Poli et al.: Microbiologia e immunologia veterinaria ed. EDRA
Materials available in the Ariel course webpages.
Giorgio Poli et al.: Microbiologia e immunologia veterinaria ed. EDRA
Materials available in the Ariel course webpages.
Assessment methods and Criteria
Multiple-choice tests presented to the student in the form of an oral examination.
Unità didattica: Immunologia
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 4
Practicals: 8 hours
Single bench laboratory practical: 8 hours
Lessons: 24 hours
Single bench laboratory practical: 8 hours
Lessons: 24 hours
Professor:
Addis Maria Filippa
Unità didattica: Microbiologia Veterinaria
VET/05 - INFECTIOUS DISEASES OF DOMESTIC ANIMALS - University credits: 2
Single bench laboratory practical: 16 hours
Lessons: 8 hours
Lessons: 8 hours
Professor:
Bonizzi Luigi
Professor(s)
Reception:
su appuntamento