Chemistry and Biochemistry
A.Y. 2023/2024
Learning objectives
The course aims to provide students with the knowledge of the fundamental concepts of chemistry and biochemistry underlying the metabolism and functionality of the organism.
Expected learning outcomes
Students:
a) know the fundamental principles of molecular, cellular and biochemical mechanisms related to the body's patho-physiology;
b) understand the importance of applying the concepts of basic research to translational research;
c) they approach critically the international scientific literature to write short review on specific topics.
a) know the fundamental principles of molecular, cellular and biochemical mechanisms related to the body's patho-physiology;
b) understand the importance of applying the concepts of basic research to translational research;
c) they approach critically the international scientific literature to write short review on specific topics.
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Course syllabus
Chemistry
Inorganic chemistry
The material and the atomic structure.
The chemical bonds between atoms and molecules.
The physical state of the material.
The aqueous solutions.
The equilibrium of the chemical reactions.
The acid and basic compounds.
The buffer compounds.
Principles of electrochemistry.
Organic Chemistry
The saturated/unsaturated hydrocarbons. Alkanes, alkenes, cycloalkanes, aromatic compounds.
Functional groups. alcohols, phenols, tio alcohols, amines, carbony compounds (aldehydes and ketones),
carboxylic acids and derivatives.
Preparatory biochemistry
The carbohydrates
The lipids
The proteins
The nucleic acids
The enzymes
Metabolic Biochemistry
Oxygen transport and chromo-proteins
Vitamins and coenzymes
Structure and functions of biological membranes
Mitochondria bioenergy
Carbohydrate metabolism and main related pathologies
Lipid Metabolism and main related pathologies
Aminoacids metabolism and main related pathologies
Insuline and Glucagone regulation of body metabolism
Hemoglobin metabolism
Nucleotides metabolism and main related pathologies
Inorganic chemistry
The material and the atomic structure.
The chemical bonds between atoms and molecules.
The physical state of the material.
The aqueous solutions.
The equilibrium of the chemical reactions.
The acid and basic compounds.
The buffer compounds.
Principles of electrochemistry.
Organic Chemistry
The saturated/unsaturated hydrocarbons. Alkanes, alkenes, cycloalkanes, aromatic compounds.
Functional groups. alcohols, phenols, tio alcohols, amines, carbony compounds (aldehydes and ketones),
carboxylic acids and derivatives.
Preparatory biochemistry
The carbohydrates
The lipids
The proteins
The nucleic acids
The enzymes
Metabolic Biochemistry
Oxygen transport and chromo-proteins
Vitamins and coenzymes
Structure and functions of biological membranes
Mitochondria bioenergy
Carbohydrate metabolism and main related pathologies
Lipid Metabolism and main related pathologies
Aminoacids metabolism and main related pathologies
Insuline and Glucagone regulation of body metabolism
Hemoglobin metabolism
Nucleotides metabolism and main related pathologies
Prerequisites for admission
High school scientific skills.
Teaching methods
Lectures, exercise training, team works.
Each CFU is composed by frontal lessons and innovative teaching time. The innovative activities consist in deepening matters that are included in the course program, in agreement with the teacher.
Chemistry module: the innovative teaching activities consist in setting up the "Sportello Chimico" in Teams mode to allow students, by appointment agreed with the teacher, to ask for additional "personalized" or small group explanations, to correct assigned exercises together, to resume parts of the program; in the assignment of a written exercise in the classroom, corrected by the teacher, which will allow students to obtain from 0.5 to 1 point, to be added to the outcome of the final exam; in carrying out a summary exercise of the topics covered, in groups, in presence, at the end of the course.
Biochemistry module: small groups of students will study a few articles from the international medical scientific literature (pubmed); present their study to the colleagues and their activity will be considered for the final exam.
Each CFU is composed by frontal lessons and innovative teaching time. The innovative activities consist in deepening matters that are included in the course program, in agreement with the teacher.
Chemistry module: the innovative teaching activities consist in setting up the "Sportello Chimico" in Teams mode to allow students, by appointment agreed with the teacher, to ask for additional "personalized" or small group explanations, to correct assigned exercises together, to resume parts of the program; in the assignment of a written exercise in the classroom, corrected by the teacher, which will allow students to obtain from 0.5 to 1 point, to be added to the outcome of the final exam; in carrying out a summary exercise of the topics covered, in groups, in presence, at the end of the course.
Biochemistry module: small groups of students will study a few articles from the international medical scientific literature (pubmed); present their study to the colleagues and their activity will be considered for the final exam.
Teaching Resources
- Santaniello E., Coletta M., Malatesta F., Zanotti G., Marini S., "Chimica Propedeutica alle scienze bio-mediche", Ed. Piccin
- Bellini T., "Chimica medica e propedeutica biochimica", Ed. Zanichelli
- Bettelheim F.A., Brown W.H., Campbell M.K., Farrell S.O., "Chimica e propedeutica biochimica", Ed. Edises
- Biochimica Medica Siliprandi e Tettamanti (PICCIN)
- Biochimica con aspetti clinici, Devlin, Edises
- Biochimica Medica , Lieberman e Marks, Casa Editrice Ambrosiana
- Bellini T., "Chimica medica e propedeutica biochimica", Ed. Zanichelli
- Bettelheim F.A., Brown W.H., Campbell M.K., Farrell S.O., "Chimica e propedeutica biochimica", Ed. Edises
- Biochimica Medica Siliprandi e Tettamanti (PICCIN)
- Biochimica con aspetti clinici, Devlin, Edises
- Biochimica Medica , Lieberman e Marks, Casa Editrice Ambrosiana
Assessment methods and Criteria
One written test with open and multiple choice questions for chemistry program and one oral test for Biochemistry program.
The written test allows the use of the periodic table of the elements and calculator for the written test. Test score will be published on Ariel website. This test score is required for the Biochemistry oral test admission, which leads to an independent score. The final score of the candidate , registered in the student career, will be obtained by the weighted average of the two scores.
The written test allows the use of the periodic table of the elements and calculator for the written test. Test score will be published on Ariel website. This test score is required for the Biochemistry oral test admission, which leads to an independent score. The final score of the candidate , registered in the student career, will be obtained by the weighted average of the two scores.
BIO/10 - BIOCHEMISTRY - University credits: 12
Lessons: 96 hours
: 48 hours
: 48 hours
Professors:
Caretti Anna, Signorelli Paola
Educational website(s)
Professor(s)
Reception:
To be defined via e-mail
c/o Osp. San Paolo, Via A. di Rudinì 8, Laboratorio di Biochimica, 9 piano, Blocco C,