Veterinary Pharmacology and Biotechnology Law
A.Y. 2023/2024
Learning objectives
Aim of the course is to provide suitable knowledge for the future biotechnologist on kinetics and dynamics of drugs and toxic compounds, specific information on the main pharmacological classes used in veterinary species and to provide understanding on the main sources and classes of toxic substances found in veterinary species. Further objectives are to provide knowledge on general principles of law and the legislation for the biotechnologist in the veterinary field and to emphasize the connection between research and scientific evaluation with the legal behavior and critical analysis on the validity of the rule of law, law application and biotechnologist's responsibilities.
Expected learning outcomes
At the end of the course the student will be able to know and understand the general principles concerning veterinary drugs and toxic substances, the mechanisms of action and the effects of the main classes of drugs and toxic substances used in the veterinary field. Furthermore, the student will be able to know and understand the general principles of law and specific legislation for the biotechnologist in the veterinary field as well as his duties and responsibilities regarding the legal standard.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
Course syllabus
LESSONS (40 HOURS)
Introduction to pharmacology and toxicology, concept of drug and toxic. Classification and toxicity of the residues. Factors influencing the activity of drugs and toxic. Mode of action of drugs and toxic. Dynamic and receptors. Kinetics of drugs and toxic: absorption, distribution, metabolism, excretion. Toxicity studies. Evaluation of the NOEL and ADI. Residues of drugs and chemicals in food. MRLs and withdrawal times of drugs in foodstuffs of animal origin. Ecotoxicity. Environmental pollution from industrial, agricultural and therapeutic origin.
General principles on the various classes of drugs and toxic: Chemotherapy of microbial infections, microbial resistance and drugs used. Antihelmintics. Antiprotozoarian drugs. Antimycotic drugs. Non-steroidal and steroidal antinflammatory drugs. Analgesics. Anti-histaminic drugs. Diuretics. Drugs acting on autonomic and somatic central nervous system. Cardiocirculatory drugs. Drugs acting on digestive tract and respiratory system.
Classes of toxics: Metals. Poisonous plants. Mycotoxins and Fumonisins. Pesticides. Rodenticides. PCB and dioxins.
SEMINARS (16 HOURS)
Visit to Pharmaco-toxicological analytical Laboratory
Seminar on kinetic studies: applying kinetic models (Computer Lab)
Seminar on animal models for drugs and toxins administrations
LESSONS (16 ORE)
Introduction to law, principles of the Italian and European institutions. The sale of transgenic animals:
-legislation on the protection of animals used for scientific purposes;
-law concerning the minimum safety and health requirements for the use of work equipment by workers at work;
-law on the legal protection of biotechnological inventions;
-Veterinary, Food and Feed Law, the general principles and requirements of food law and food safety; EC Regulation no. 178/2002 on Food Security and the EU Reg. No. 2283/2015 relating to novel foods.
-law on procedures for the authorisation and supervision of medicinal products for veterinary use;
-law on the provision of food information to consumers and feed;
-legislation on genetically modified food and feed.
The nanotechnology: legislation on engineered nanomaterials in the food and feed sector, and approaches for safety assessment;
-law on use of stem cells in veterinary medicine.
-environmental law.
SEMINARS (16 HOURS)
Drafting of security protocols in laboratories.
Seminars on EFSA opinions on GMOs, engineered nanotechnology in feed and food
Analysis of EFSA opinions on the environmental impact assessment.
Introduction to pharmacology and toxicology, concept of drug and toxic. Classification and toxicity of the residues. Factors influencing the activity of drugs and toxic. Mode of action of drugs and toxic. Dynamic and receptors. Kinetics of drugs and toxic: absorption, distribution, metabolism, excretion. Toxicity studies. Evaluation of the NOEL and ADI. Residues of drugs and chemicals in food. MRLs and withdrawal times of drugs in foodstuffs of animal origin. Ecotoxicity. Environmental pollution from industrial, agricultural and therapeutic origin.
General principles on the various classes of drugs and toxic: Chemotherapy of microbial infections, microbial resistance and drugs used. Antihelmintics. Antiprotozoarian drugs. Antimycotic drugs. Non-steroidal and steroidal antinflammatory drugs. Analgesics. Anti-histaminic drugs. Diuretics. Drugs acting on autonomic and somatic central nervous system. Cardiocirculatory drugs. Drugs acting on digestive tract and respiratory system.
Classes of toxics: Metals. Poisonous plants. Mycotoxins and Fumonisins. Pesticides. Rodenticides. PCB and dioxins.
SEMINARS (16 HOURS)
Visit to Pharmaco-toxicological analytical Laboratory
Seminar on kinetic studies: applying kinetic models (Computer Lab)
Seminar on animal models for drugs and toxins administrations
LESSONS (16 ORE)
Introduction to law, principles of the Italian and European institutions. The sale of transgenic animals:
-legislation on the protection of animals used for scientific purposes;
-law concerning the minimum safety and health requirements for the use of work equipment by workers at work;
-law on the legal protection of biotechnological inventions;
-Veterinary, Food and Feed Law, the general principles and requirements of food law and food safety; EC Regulation no. 178/2002 on Food Security and the EU Reg. No. 2283/2015 relating to novel foods.
-law on procedures for the authorisation and supervision of medicinal products for veterinary use;
-law on the provision of food information to consumers and feed;
-legislation on genetically modified food and feed.
The nanotechnology: legislation on engineered nanomaterials in the food and feed sector, and approaches for safety assessment;
-law on use of stem cells in veterinary medicine.
-environmental law.
SEMINARS (16 HOURS)
Drafting of security protocols in laboratories.
Seminars on EFSA opinions on GMOs, engineered nanotechnology in feed and food
Analysis of EFSA opinions on the environmental impact assessment.
Prerequisites for admission
None
Teaching methods
Frontal lessons in pharmacology and veterinary toxicology (5 cfu) and tutorials (1 cfu),
Frontal lessons in biotechnology law (2 cfu) and tutorials (1 cfu)
Language of teaching: Italian
Frontal lessons in biotechnology law (2 cfu) and tutorials (1 cfu)
Language of teaching: Italian
Teaching Resources
· Carli S., Ormas P., Re G., Soldani G. (2010) Farmacologia Veterinaria, 1a edizione, Idelson-Gnocchi Editore, Napoli
· Clementi e Fumagalli. Farmacologia generale e molecolare (2007), 3° ed. UTET.
· Mengozzi e Soldani, Tossicologia Veterinaria (2010), Idelson-Gnocchi
· Nebbia, Residui di farmaci e contaminanti ambientali nelle produzioni animali (2009), Ed. EdiSES
· C. Beretta:Tossicologia Veterinaria. Editoriale Grasso Bologna 1984.
· DIRITTO E LEGISLAZIONE VETERINARIA, F. Pezza-G. Ruffo-P.Fossati, Point Veterinaire Italie, Milano.
·Handout with updates provided directly by Teachers
· Clementi e Fumagalli. Farmacologia generale e molecolare (2007), 3° ed. UTET.
· Mengozzi e Soldani, Tossicologia Veterinaria (2010), Idelson-Gnocchi
· Nebbia, Residui di farmaci e contaminanti ambientali nelle produzioni animali (2009), Ed. EdiSES
· C. Beretta:Tossicologia Veterinaria. Editoriale Grasso Bologna 1984.
· DIRITTO E LEGISLAZIONE VETERINARIA, F. Pezza-G. Ruffo-P.Fossati, Point Veterinaire Italie, Milano.
·Handout with updates provided directly by Teachers
Assessment methods and Criteria
The exam consists of a single oral test on the knowledge of the topics described in the two modules
Biotechnology law and patents
VET/07 - VETERINARY PHARMACOLOGY AND TOXICOLOGY
VET/08 - VETERINARY CLINICAL MEDICINE
VET/08 - VETERINARY CLINICAL MEDICINE
Practicals: 16 hours
Lessons: 16 hours
Lessons: 16 hours
Professor:
Ruffo Giancarlo
Veterinary Pharmacology and Toxicology
VET/07 - VETERINARY PHARMACOLOGY AND TOXICOLOGY
VET/08 - VETERINARY CLINICAL MEDICINE
VET/08 - VETERINARY CLINICAL MEDICINE
Practicals: 8 hours
Single bench laboratory practical: 8 hours
Lessons: 40 hours
Single bench laboratory practical: 8 hours
Lessons: 40 hours
Professor:
Cagnardi Petra Pico'