Biochemical-Molecular Mechanisms of Action of Pollutants On Human Health

The course aims to provide knowledge on the human environment-body interaction, analyzing the mechanisms of action by which pollutants and global warming interfere with the regulation of metabolic and physiological processes with consequences relevant to human health.

The student will acquire knowledge related to the main biochemical-molecular aspects underlying the biotransformation processes of xenobiotics and related molecular mechanisms of biotransformation regulation, which may be the cause of their toxicity.
At the end of the course the student should be able:
1. to illustrate the relevance of the interaction of environment and health.
2. to define the biochemical mechanisms responsible for physiological adaptation to different environmental conditions.
3. to define the mechanisms of action and signaling pathways by which specific pollutants and global warming interfere with the regulation of metabolic and physiological processes with consequences relevant to human health.