Functional Genomics
A.Y. 2025/2026
Learning objectives
The aim of the course is to discuss the criteria and the methods to design or improve a biotechnological process exploiting plant cells or whole plants to produce biomass or substances of industrial or environmental relevance (e.g. biofuels, oils, detergents, vitamins, starch, sugars, biodegradable polymers). An 'on-site' visit to at least one company or research centre is envisaged to make the students aware about plant biotechnology outside the academic environment.
The course is ideally linked to those dealing with functional genomics and other "-omic" technologies, plant breeding, molecular enzymology, bioinformatics and data analysis.
The course is ideally linked to those dealing with functional genomics and other "-omic" technologies, plant breeding, molecular enzymology, bioinformatics and data analysis.
Expected learning outcomes
Upon completing this course, students will acquire substantial knowledge on metabolic fluxes, on strategies that can be used to modify yield and on the tools available in plant biotechnology to achieve the objectives.
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course can be attended as a single course.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
Course syllabus
Whole genome sequencing
Genome annotation
Gene family analysis
Reverse genetics strategies in prokaryotes and eukaryotes
Genome editing strategies
Transcriptomics (incl. spatial)
Small non-coding RNA function and their analysis
Regulatory pathway analysis
Proteomics strategies
Protein interactions and complex formation
Protein analysis in living cells.
Genome annotation
Gene family analysis
Reverse genetics strategies in prokaryotes and eukaryotes
Genome editing strategies
Transcriptomics (incl. spatial)
Small non-coding RNA function and their analysis
Regulatory pathway analysis
Proteomics strategies
Protein interactions and complex formation
Protein analysis in living cells.
Prerequisites for admission
Good basic knowledge of Molecular Biology and Genetics.
Teaching methods
Frontal lectures. At the end of the course, there will be an additional question time during which students can ask for extra explanations regarding all the topics that were discussed during the lessons.
Teaching Resources
Scientific papers and video's will be presented during lectures and all materials will be uploaded on the Ariel website, lecture attendance is strongly encouraged.
Assessment methods and Criteria
Learning assessment will be through a written exam at the end of the course. The examination will consist of 6 open questions of which, students must answer 5. Each question contributes equally to the final score. The students will have 2 hours to answer the question.
BIO/18 - GENETICS - University credits: 6
Lectures: 48 hours
Educational website(s)
Professor(s)
Reception:
Thursday 14.00 - 17.00
Via Celoria 26, Tower B, 2nd floor