Patologia e terapia medica

A.Y. 2025/2026
6
Max ECTS
60
Overall hours
SSD
BIO/14 MED/04 MED/05
Language
Italian
Learning objectives
- Acquire knowledge of the fundamental principles of general pathology and general pathophysiology.
- Develop the ability to analyze the causes (etiology) and mechanisms (pathogenesis) underlying the onset and progression of disease.
- Gain an understanding of diagnostic-clinical pathology and laboratory methodologies in cytology, cytopathology, immunohematology, and genetic pathology.
- Understand the laboratory diagnostic approaches to major pathological conditions and their associated biomarkers.
- Acquire knowledge of the diagnostic-clinical aspects of reproductive medicine.
- Understand the principles of general pharmacology, including pharmacodynamics and pharmacokinetics.
- Develop knowledge of major drug interactions, as well as the principles of pharmacogenetics and pharmacovigilance.
Expected learning outcomes
The course aims to provide the necessary knowledge for understanding the causes of human diseases and the fundamental pathogenetic mechanisms at the cell and tissue levels. At the end of the course the students will have a good knowledge of etiology and pathogenesis with particular reference to the main genetic diseases, the various forms of the inflammatory process, the damage, the main alterations of the immune system, and the tumors.
The course gives the knowledge of clinical biomarkers use in clinical practice. The students will have the acquaintance of the main biomarkers currently approved in Laboratory Medicine to discriminate the health state than a pathological status and its development. The students will also have learned the main diagnostic tools and clinical exams used to identify the health state from prenatal phase to the childhood.
Students will be able to understand the fundamental principles of pharmacodynamics and pharmacokinetics, applying them to the evaluation of drug efficacy and safety. In addition, they will acquire competencies in pharmacological interactions, pharmacogenetics, and pharmacovigilance tools, which are essential for safe and evidence-based clinical practice.
Single course

This course can be attended as a single course.

Course syllabus and organization

Sezione: Bosisio Parini

Responsible
Prerequisites for admission
The prerequisites consist of physiology, anatomical, histological, biochemical and biological knowledge that are study subject of the first year of the course.
Assessment methods and Criteria
The examination consists of a written test with multiple choice questions aimed at assessing the student's knowledge of the different topics covered.
The evaluation is expressed in thirtieths and the result is communicated after the conclusion of the test.
Farmacologia
Course syllabus
- Receptor drug interactions
- Effect of drugs, receptor agonists and antagonists - Generalities on receptors - Main classes of receptors - Desensitization and downregulation of receptors
- General principles of pharmacokinetics: absorption, distribution, metabolism and elimination of drugs.
- Drug interactions
- Clinical drug development and Pharmacovigilance
- Pharmacogenetics
- NSAIDs
- Corticosteroids and related receptors
- Rare diseases and dystrophies
- Central nervous system pharmacology
- Anxiolytic and antidepressant drugs and their use in childhood.
- Antipsychotic and Mood stabilizer drugs and their use in childhood.
- Antiepilectic drugs and their use in childhood.
Teaching methods
Lectures (30 hours) of a dialectical type supported by PowerPoint presentations
Teaching Resources
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana), Zanichelli editore;
Govoni - Farmacologia, Casa editrice Ambrosiana
Patologia generale
Course syllabus
Experimental medicine and pathophysiolog
Course syllabus
Introduction of general pathology and cell death
- Etiology
- Immunology
- Inflammation
- Atherosclerosis and damage response
- Pathophysiology of the Blood
- Tumors
Teaching methods
Lectures (20 hours). All the lectures are supported by PowerPoint presentations.
Teaching Resources
Jeanette Anne Marie Maier, ed. Mc Graw Hill Education, Patologia Generale e Fisiopatologia per le professioni sanitarie
Patologia clinica
Course syllabus
The student at the end of the clinical pathology course will be able to:
- describe the basic concepts of laboratory medicine;
- identify the main biomarkers of health and disease status;
- classify the different organ biomarkers;
- critically interpret the laboratory data.
Teaching methods
Lectures (20 hours). All the lectures are supported by PowerPoint presentations, made available to the students.
Teaching Resources
Slides provided by the teacher integrated with the following books:
Italo Antognozzi, Elio Gulletta, Medicina di laboratorio-logica & Patologia Clinica- II edizione- Piccin.
Widmann - Interpretazione clinica degli esami di laboratorio- 11 edizione- McGraw-Hill
Modules or teaching units
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 3
Lessons: 30 hours

Patologia clinica
MED/05 - CLINICAL PATHOLOGY - University credits: 1
Lessons: 10 hours
Professor: Vianello Elena

Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 20 hours
Professor: Castiglioni Sara

Sezione: Don Gnocchi

Prerequisites for admission
The prerequisites consist of physiology, anatomical, histological, biochemical and biological knowledge that are study subject of the first year of the course.
Assessment methods and Criteria
The examination consists of a written test with multiple choice questions aimed at assessing the student's knowledge of the different topics covered.
The evaluation is expressed in thirtieths and the result is communicated after the conclusion of the test.
Farmacologia
Course syllabus
- Receptor drug interactions
- Effect of drugs, receptor agonists and antagonists - Generalities on receptors - Main classes of receptors - Desensitization and downregulation of receptors
- General principles of pharmacokinetics: absorption, distribution, metabolism and elimination of drugs.
- Drug interactions
- Clinical drug development and Pharmacovigilance
- Pharmacogenetics
- NSAIDs
- Corticosteroids and related receptors
- Rare diseases and dystrophies
- Central nervous system pharmacology
- Anxiolytic and antidepressant drugs and their use in childhood.
- Antipsychotic and Mood stabilizer drugs and their use in childhood.
- Antiepilectic drugs and their use in childhood.
Teaching methods
Lectures (30 hours) of a dialectical type supported by PowerPoint presentations
Teaching Resources
Whalen K. Le basi della Farmacologia. (3ed italiana condotta sulla settima edizione americana), Zanichelli editore;
Govoni - Farmacologia, Casa editrice Ambrosiana
Patologia generale
Course syllabus
Introduction of general pathology and cell death
- Etiology
- Immunology
- Inflammation
- Atherosclerosis and damage response
- Pathophysiology of the Blood
- Tumors
Teaching methods
Lectures (20 hours). All the lectures are supported by PowerPoint presentations.
Teaching Resources
Jeanette Anne Marie Maier, ed. Mc Graw Hill Education, Patologia Generale e Fisiopatologia per le professioni sanitarie
Patologia clinica
Course syllabus
The student at the end of the clinical pathology course will be able to:
- describe the basic concepts of laboratory medicine;
- identify the main biomarkers of health and disease status;
- classify the different organ biomarkers;
- critically interpret the laboratory data.
Teaching methods
Lectures (20 hours). All the lectures are supported by PowerPoint presentations, made available to the students.
Teaching Resources
Slides provided by the teacher integrated with the following books:
Italo Antognozzi, Elio Gulletta, Medicina di laboratorio-logica & Patologia Clinica- II edizione- Piccin.
Widmann - Interpretazione clinica degli esami di laboratorio- 11 edizione- McGraw-Hill
Modules or teaching units
Farmacologia
BIO/14 - PHARMACOLOGY - University credits: 3
Lessons: 30 hours
Professor: Perrotta Cristiana

Patologia clinica
MED/05 - CLINICAL PATHOLOGY - University credits: 1
Lessons: 10 hours
Professor: Vianello Elena

Patologia generale
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY - University credits: 2
Lessons: 20 hours
Professor: Castiglioni Sara

Professor(s)
Reception:
on appointment to be organised via e-mail
"Palazzina LITA-Vialba"
Reception:
after fixing an appointment by e-mail.
31 Luigi Mangiagalli street, Milan, Italy, 20133