Pharmacology 1 and Pharmacology 2
A.Y. 2025/2026
Learning objectives
- Understand the cellular and molecular basics of pharmacology
- Provide adequate knowledge on the major drugs classes, both small molecules and biologicals.
- Provide adequate knowledge on the major drugs classes, both small molecules and biologicals.
Expected learning outcomes
At the end of the course, the student will have acquired the Knowledge and understanding of the main fundamentals of pharmacology, including pharmacodynamics, drug safety and toxicity
Lesson period: year
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
year
Course syllabus
Pharmacology 1
Receptors: main classes, definition and characteristics. Ionotropic receptors (channel receptor). Tyrosine kinase-coupled receptors (receptors for growth factors). Metabotropic G-protein-coupled receptors. Intracellular signal transduction. Post-translational modifications (phosphorylation and sumoylation). Intracellular receptors. Adhesion molecules. Rules and principles of drug-receptor interaction. Voltage-dependent ion channels (VOC). Main neurotransmitter systems, glutamatergic, gabaergic, cholinergic systems.
Pharmacology 2
Dopaminergic transmission and drugs for Parkinson's disease. Drugs for Alzheimer's disease. Anti-epileptic drugs. Benzodiazepines and other anxiolytic drugs. Serotoninergic system and drugs for Depression. Schizophrenia and antipsychotic drugs. Biotechnological drugs, main pharmacokinetic and pharmacodynamic characteristics, efficacy and adverse effects. Non-steroidal anti-inflammatory drugs (NSAIDs). Cortisonics. Classical and biotechnological drugs for rheumatoid arthritis. Medications for the treatment of multiple sclerosis. Anti-asthmatic drugs. Hyperlipidaemias and therapy. Anti-diabetic drugs. Drugs for the treatment of pain, opioid analgesics and migraine drugs. Antibiotics. Drugs for the treatment of neoplasms. Drugs for the treatment of hypertension. Antiplatelet and anticoagulant drugs. Antiviral drugs. Vaccines.
Receptors: main classes, definition and characteristics. Ionotropic receptors (channel receptor). Tyrosine kinase-coupled receptors (receptors for growth factors). Metabotropic G-protein-coupled receptors. Intracellular signal transduction. Post-translational modifications (phosphorylation and sumoylation). Intracellular receptors. Adhesion molecules. Rules and principles of drug-receptor interaction. Voltage-dependent ion channels (VOC). Main neurotransmitter systems, glutamatergic, gabaergic, cholinergic systems.
Pharmacology 2
Dopaminergic transmission and drugs for Parkinson's disease. Drugs for Alzheimer's disease. Anti-epileptic drugs. Benzodiazepines and other anxiolytic drugs. Serotoninergic system and drugs for Depression. Schizophrenia and antipsychotic drugs. Biotechnological drugs, main pharmacokinetic and pharmacodynamic characteristics, efficacy and adverse effects. Non-steroidal anti-inflammatory drugs (NSAIDs). Cortisonics. Classical and biotechnological drugs for rheumatoid arthritis. Medications for the treatment of multiple sclerosis. Anti-asthmatic drugs. Hyperlipidaemias and therapy. Anti-diabetic drugs. Drugs for the treatment of pain, opioid analgesics and migraine drugs. Antibiotics. Drugs for the treatment of neoplasms. Drugs for the treatment of hypertension. Antiplatelet and anticoagulant drugs. Antiviral drugs. Vaccines.
Prerequisites for admission
Knowledge of Physiology and Pathology is an important aspect in order to deal adequately with the teaching content
Teaching methods
Frontal lectures
Teaching Resources
General and molecular pharmacology - Clementi, Fumagalli, Utet-Edra. All slides used during the lectures will be available on the Ariel website.
Assessment methods and Criteria
Oral examination. The examination is generally based on 3-4 open questions. Particular attention will be paid to knowledge of the mechanisms of action and adverse effects of the main drug classes. The grade is expressed in thirtieths.
Professor(s)
Reception:
Monday 9.00 a.m.
Via Balzaretti 9, DiSFeB