New Methodologies for Synthesis and Modification of Natural Products

The lecture course "New Methodologies for Synthesis and Modification of Natural products" will cover a range of methods in organic chemistry relevant to the synthesis of complex bioactive molecules. The course content is structured in multiple sections. The first section covers modern synthetic methods, with an emphasis on asymmetric synthesis and carbon-carbon bond formation. The focus of this section is on models for understanding the stereochemical outcomes of reactions and the application of these techniques to design synthetic strategies towards complex target molecules. The second section is focused on retrosynthetic analysis, a powerful conceptual tool chemists use to design synthetic strategies. In the final part of the course, a recent synthesis of a complex natural product will be presented, thus giving an opportunity to appreciate applications in a real-life context, while introducing students to state-of-the-art synthetic methodologies and tactics. This course will be held by lecturers expert in total synthesis and novel synthetic methodologies.