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High-throughput biology

A.A. 2019/2020
6
Crediti massimi
48
Ore totali
SSD
BIO/13
Lingua
Inglese
Obiettivi formativi
- After completion of this course, students should be able to better understand and compare different high throughput methods used, for instance, for the discovery and validation of new biomarkers.
- Be able to present this knowledge in oral and written form.
Risultati apprendimento attesi
Non definiti

Periodo: Primo semestre

Orari delle lezioni

Modalità di valutazione: Esame
Giudizio di valutazione: voto verbalizzato in trentesimi

Calendario degli appelli

Corso singolo

Questo insegnamento non può essere seguito come corso singolo. Puoi trovare gli insegnamenti disponibili consultando il catalogo corsi singoli.

Cerca un corso singolo
Programma e organizzazione didattica

Edizione unica


Programma
The lectures present the basic methodology and some advanced techniques used for high throughput in vitro small molecule drug discovery. The principles and statistical methods used for assay optimization and validation will also be explained.
I. Molecular biology, Biochemistry and Protein expression
II. Proteomic analysis; Mass spectrometry
III. Lab-chips and Cell-chips
IV. Structural biology: Crystallogenesis and Crystallization; RMN
V. Combinatory chemistry
Prerequisiti
Background in biochemistry, molecular biology and cellular biology. Knowledge in physiology, immunology and microbiology will be appreciated. Students with laboratory and/or practical skills will better understand technological benefits of the use of high throughput technologies in the lab work.
Final exam: Oral exam (at the end of December; 50%) and Research project (at the beginning of January; 50%).
Metodi didattici
Lectures
Sito
BIO/13 - BIOLOGIA APPLICATA - CFU: 6
Lectures: 48 ore
Docente: Cherrier MickaËl
Turni:
-
Docente: Cherrier MickaËl