High-Throughput Biology
A.Y. 2019/2020
Learning objectives
- After completion of this course, students should be able to better understand and compare different high throughput methods used, for instance, for the discovery and validation of new biomarkers.
- Be able to present this knowledge in oral and written form.
- Be able to present this knowledge in oral and written form.
Expected learning outcomes
Undefined
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Course syllabus
The lectures present the basic methodology and some advanced techniques used for high throughput in vitro small molecule drug discovery. The principles and statistical methods used for assay optimization and validation will also be explained.
I. Molecular biology, Biochemistry and Protein expression
II. Proteomic analysis; Mass spectrometry
III. Lab-chips and Cell-chips
IV. Structural biology: Crystallogenesis and Crystallization; RMN
V. Combinatory chemistry
Prerequisites and examination procedures:
Prerequisites
Background in biochemistry, molecular biology and cellular biology. Knowledge in physiology, immunology and microbiology will be appreciated. Students with laboratory and/or practical skills will better understand technological benefits of the use of high throughput technologies in the lab work.
Examination procedures
· Final exam: Oral exam (at the end of December; 50%) and Research project (at the beginning of January; 50%)
Teaching Methods
Lectures
Language of instruction
English
WEB pages
https://master-biologie.univ-grenoble-alpes.fr/majors/planta-international-plant-int-/
I. Molecular biology, Biochemistry and Protein expression
II. Proteomic analysis; Mass spectrometry
III. Lab-chips and Cell-chips
IV. Structural biology: Crystallogenesis and Crystallization; RMN
V. Combinatory chemistry
Prerequisites and examination procedures:
Prerequisites
Background in biochemistry, molecular biology and cellular biology. Knowledge in physiology, immunology and microbiology will be appreciated. Students with laboratory and/or practical skills will better understand technological benefits of the use of high throughput technologies in the lab work.
Examination procedures
· Final exam: Oral exam (at the end of December; 50%) and Research project (at the beginning of January; 50%)
Teaching Methods
Lectures
Language of instruction
English
WEB pages
https://master-biologie.univ-grenoble-alpes.fr/majors/planta-international-plant-int-/
BIO/13 - EXPERIMENTAL BIOLOGY - University credits: 6
Lectures: 48 hours
Professor:
Cherrier MickaËl
Shifts:
-
Professor:
Cherrier MickaËl