Bioinformatics and molecular modeling

A.A. 2020/2021
8
Crediti massimi
64
Ore totali
SSD
BIO/10 CHIM/06 CHIM/08
Lingua
Inglese
Obiettivi formativi
The purpose of this course is that participants gain knowledge on and understand:
- the prediction of the principal physicochemical and structural properties of pharmacological targets and of biotechnological drugs and products;
- the accuracy of in silico approaches used in the development of biotechnological drugs and products;
- the computational strategies for modelling targets, responsible for biological activity, simulating their interaction with biotechnological drugs and their molecular recognition mechanisms at an atomistic level;
methods to predict and validate the mechanism of action of biotechnological drugs and products, with particular attention to a better rational design of experiments on animal models, according to the 3Rs principle.
Risultati apprendimento attesi
At the end of the course, the student is expected to know:
- the application of the computational methods used in biotechnological research;
to critically evaluate:
- the pros and cons of in silico prediction approaches used for developing biotechnological drugs and products;
to gain:
- the bases for deeply understanding computational methods and results described in scientific literature;
to obtain:
a multifaceted bioinformatics knowledgebase, useful for further student's personal study of this topic.
Programma e organizzazione didattica

Edizione unica

Responsabile
Periodo
Secondo semestre
Moduli o unità didattiche
Data modeling in biotechnology
BIO/10 - BIOCHIMICA - CFU: 0
CHIM/06 - CHIMICA ORGANICA - CFU: 0
CHIM/08 - CHIMICA FARMACEUTICA - CFU: 0
Lezioni: 24 ore

Molecular mechanics and dynamics
BIO/10 - BIOCHIMICA - CFU: 0
CHIM/06 - CHIMICA ORGANICA - CFU: 0
CHIM/08 - CHIMICA FARMACEUTICA - CFU: 0
Lezioni: 16 ore

Structural bioinformatics
BIO/10 - BIOCHIMICA - CFU: 0
CHIM/06 - CHIMICA ORGANICA - CFU: 0
CHIM/08 - CHIMICA FARMACEUTICA - CFU: 0
Lezioni: 24 ore
Docente: Eberini Ivano

Docente/i
Ricevimento:
Su appuntamento
Dipartimento di Scienze Molecolari Applicate ai Biosistemi, via Venezian, 21, 20133 Milano, terzo piano
Ricevimento:
Su appuntamento
Dipartimento di Scienze Farmacologiche e Biomolecolari, Via Giuseppe Balzaretti, 9 - 20133 Milano