Radiomics

A.A. 2020/2021
6
Crediti massimi
48
Ore totali
SSD
MED/04 MED/36
Lingua
Inglese
Obiettivi formativi
Non definiti
Risultati apprendimento attesi
Non definiti
Programma e organizzazione didattica

Edizione unica

Responsabile
Programma
1. Radiobiology
Interactions of ionising radiation with matter
Radiation effects on healthy and tumor tissue
Radiosensitivity and radioresistance of tissue

2. Imaging acquisition techniques:
Digital diagnostic images: matrix, spatial resolution, contrast resolution, archive and distribution. Processing of digital images.
Mechanical waves and ultrasound image formation. Doppler phenomenon. Ultrasound contrast media and harmonic imaging.
Computerized tomography: technological evolution of the equipment, reconstruction through sinograms and back projection.
Hounsfield unit and window concept.
Magnetic Resonance: signal genesis, relaxation time T1 and T2, spatial encoding.
Contrast agents in radiology and MRI

3. Oncological radiotherapy
Indications to radiotherapy in the most common solid tumors and hematological malignancies
Radiotherapy devices and modalities
Work flow in radiotherapy
Image guided radiotherapy
Tumor remission and normal tissue toxicity

4. Images are numbers:
Radiomic goals
Radiologic images are biomarkers for oncologic response evaluation and for response prediction
Radiomic pathways:
Target lesions identification
Target lesions contouring
Extraction of target lesions
Radiomic analysis
Radiomic features description
Radiomic features variability and causes of variability

5. Radiomics and radiogenomics
Clinical applications
Treatment personalisation
Methodological challenges
Prerequisiti
Non sono richieste conoscenze preliminari.
Metodi didattici
Il corso verrà svolto tramite lezioni frontali che verranno rese disponibili su Ariel
Alle lezioni frontali saranno affiancate esercitazioni, lavori di gruppo e spazi di riflessione e discussione.
Materiale di riferimento
Radiomics and Radiogenomics: Technical Basis and Clinical Applications (Imaging in Medical Diagnosis and Therapy) 1st Edition
By Ruijiang Li, Lei Xing, Sandy Napel, Daniel L. Rubin
ISBN 9780815375852
Published June 28, 2019 by Chapman and Hall/CRC
Modalità di verifica dell’apprendimento e criteri di valutazione
La verifica dell'apprendimento avverrà tramite esami orali che verificheranno le conoscenze sugli argomenti trattati a lezione.
MED/04 - PATOLOGIA GENERALE - CFU: 0
MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA - CFU: 0
Lezioni: 48 ore
Siti didattici
Docente/i
Ricevimento:
previo appuntamento da concordare via e-mail
IEO via Ripamonti 435, Milano
Ricevimento:
Martedì e Giovedì ore 12 previo appuntamento