Functional Genomics and the Molecular Basis of Differentiation
A.Y. 2018/2019
Learning objectives
The objective of the course is to provide students with: 1) a general overview on the principal methods for the study of bacterial genomes (genome sequencing techniques, genome annotation, phylogenetic studies); a general overview on the single cell genomic and trancriptomic techniques; 3) information and training in the advances in the understanding of the molecular basis of genomic and epigenetic mechanisms in gene expression in livestock species.
Expected learning outcomes
Undefined
Lesson period: First semester
Assessment methods: Esame
Assessment result: voto verbalizzato in trentesimi
Single course
This course cannot be attended as a single course. Please check our list of single courses to find the ones available for enrolment.
Course syllabus and organization
Single session
Responsible
Lesson period
First semester
ATTENDING STUDENTS
NON-ATTENDING STUDENTS
Unit: Genomics and epigenetics in vertebrates
Course syllabus
Genes, markers and the genome
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
Course syllabus
Single cell genome sequencing: 1) Single cell isolation methods; 2) Cell lysis and gDNA extraction; 3) Whole genome amplification (MDA).
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Unit: Genomics and epigenetics in vertebrates
Course syllabus
Genes, markers and the genome
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
Course syllabus
Single cell genome sequencing: 1) Single cell isolation methods; 2) Cell lysis and gDNA extraction; 3) Whole genome amplification (MDA).
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Unit: Genomics and epigenetics in vertebrates
AGR/17 - LIVESTOCK SYSTEMS, ANIMAL BREEDING AND GENETICS
VET/06 - PARASITOLOGY AND ANIMAL PARASITIC DISEASES
VET/06 - PARASITOLOGY AND ANIMAL PARASITIC DISEASES
Practicals: 12 hours
Lessons: 18 hours
Lessons: 18 hours
Professor:
Minozzi Giulietta
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
AGR/17 - LIVESTOCK SYSTEMS, ANIMAL BREEDING AND GENETICS
VET/06 - PARASITOLOGY AND ANIMAL PARASITIC DISEASES
VET/06 - PARASITOLOGY AND ANIMAL PARASITIC DISEASES
Practicals: 24 hours
Lessons: 12 hours
Lessons: 12 hours
Professor:
Bazzocchi Chiara
Professor(s)
Reception:
Every day by appointment
Department of veterinary Medicine and Animal Science