Functional genomics and the molecular basis of differentiation
A.A. 2018/2019
Obiettivi formativi
The objective of the course is to provide students with: 1) a general overview on the principal methods for the study of bacterial genomes (genome sequencing techniques, genome annotation, phylogenetic studies); a general overview on the single cell genomic and trancriptomic techniques; 3) information and training in the advances in the understanding of the molecular basis of genomic and epigenetic mechanisms in gene expression in livestock species.
Risultati apprendimento attesi
Non definiti
Periodo: Primo semestre
Modalità di valutazione: Esame
Giudizio di valutazione: voto verbalizzato in trentesimi
Corso singolo
Questo insegnamento non può essere seguito come corso singolo. Puoi trovare gli insegnamenti disponibili consultando il catalogo corsi singoli.
Programma e organizzazione didattica
Edizione unica
Responsabile
Periodo
Primo semestre
STUDENTI FREQUENTANTI
STUDENTI NON FREQUENTANTI
Prerequisiti
Modalità esame: scritto
Unit: Genomics and epigenetics in vertebrates
Programma
Genes, markers and the genome
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
Metodi didattici
Corso in aula ed esercitazioni
Materiale di riferimento
Livestock Epigenetics
Hasan Khatib (Editor)
ISBN: 978-0-470-95859-9
February 2012, Wiley-Blackwell
Hasan Khatib (Editor)
ISBN: 978-0-470-95859-9
February 2012, Wiley-Blackwell
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
Programma
Single cell genome sequencing: 1) Single cell isolation methods; 2) Cell lysis and gDNA extraction; 3) Whole genome amplification (MDA).
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Metodi didattici
Corso in aula ed esercitazioni
Materiale di riferimento
Materiale fornito direttamente dal docente
Prerequisiti
Modalità esame: scritto
Unit: Genomics and epigenetics in vertebrates
Programma
Genes, markers and the genome
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
DNA and RNA , sequencing technologies available today
Epigenetics of Mammalian Gamete and Embryo Development
Epigenetics of Cloned Preimplantation Embryos of Domestic
Roles of Imprinted Genes in Fertility and Promises of the Genome-Wide technologies .
Genomic Imprinting and Imprinted Gene Clusters in the Bovine Genome
Epigenetics and Animal Health
Epigenetics and microRNAs in Animal Health
Materiale di riferimento
Livestock Epigenetics
Hasan Khatib (Editor)
ISBN: 978-0-470-95859-9
February 2012, Wiley-Blackwell
Hasan Khatib (Editor)
ISBN: 978-0-470-95859-9
February 2012, Wiley-Blackwell
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
Programma
Single cell genome sequencing: 1) Single cell isolation methods; 2) Cell lysis and gDNA extraction; 3) Whole genome amplification (MDA).
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Single cell transcriptomics: methods and applications.
Next generation sequencing techniques.
Application of NGS to the analysis of microbiome and bacterial transcriptome.
Study of bacterial genome evolution by the use of phylogenetic analysis.
Pratic lessons:
Use of LINUX operating system.
Assembly, annotation and phylogenesis of procariotic genomes.
Analysis of metagenomic data obtained after a shutgun approach.
Materiale di riferimento
Materiale didattico fornito direttamente dal docente
Moduli o unità didattiche
Unit: Genomics and epigenetics in vertebrates
AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICO
VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
Esercitazioni: 12 ore
Lezioni: 18 ore
Lezioni: 18 ore
Docente:
Minozzi Giulietta
Unit: Genomics and molecular basis of differentiation in model invertebrate organisms and pathogens
AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICO
VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
Esercitazioni: 24 ore
Lezioni: 12 ore
Lezioni: 12 ore
Docente:
Bazzocchi Chiara
Docente/i
Ricevimento:
Tutti i giorni su appuntamento
Dipartimento di Medicina Veterinaria e Scienze Animali